5392-10-9

Basic information

• Product Name: 6-Bromoveratraldehyde
• Synonyms: 6-BROMOVERATRALDEHYDE;AKOS B005109;TIMTEC-BB SBB003186;6-BROMOVEZATALDEHYDE;2-BROMO-4,5-DIMETHOXYBENZALDEHYDE / 6-BROMOVERATRALDEHYDE;6-BROMOVERATRALDEHYDE 98%;2-BROMO-4,5-DIMETHOXYBENZALEHYDE;4,5-Dimethoxy-2-bromobenzaldehyde
• CAS NO: 5392-10-9
• Molecular Formula: C₉H₉BrO₃
• Molecular Weight: 245.07
• EINECS: 226-390-4
• Product Categories: Aromatic Aldehydes & Derivatives (substituted);Benzaldehyde;Aldehydes;C9;Carbonyl Compounds
• Mol File: 5392-10-9.mol
• Article Data: 75

Chemical Properties

• Melting Point: 150-151 °C(lit.)
• Boiling Point: 316.1 °C at 760 mmHg
• Flash Point: 145 °C
• Appearance: white to light yellow crystals or powder
• Density: 1.5955 (rough estimate)
• Vapor Pressure: 0.000418mmHg at 25°C
• Refractive Index: 1.4730 (estimate)
• Storage Temp.: Room temperature.
• Water Solubility: Insoluble in water.
• Sensitive: Air Sensitive
• BRN: 2052355
• CAS DataBase Reference: 6-Bromoveratraldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Bromoveratraldehyde(5392-10-9)
• EPA Substance Registry System: 6-Bromoveratraldehyde(5392-10-9)

Safety Data

• Hazard Codes: Xi
• Safety Statements: 24/25
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 5392-10-9(Hazardous Substances Data)

Usage

Description

6-Bromoveratraldehyde is an organic compound characterized by its white to light yellow crystalline or powdery appearance. It is a derivative of veratraldehyde, featuring a bromine atom at the 6th position, which imparts unique chemical properties to the molecule.

Uses

Used in Pharmaceutical Industry:
6-Bromoveratraldehyde is used as an intermediate in the synthesis of various pharmaceutical compounds, specifically benzylchromenylamines. These compounds have potential applications in the development of new drugs due to their diverse chemical structures and biological activities.
Used in Chemical Synthesis:
In the field of organic chemistry, 6-Bromoveratraldehyde serves as a valuable building block for the creation of more complex molecules. Its bromine atom can be involved in various chemical reactions, such as substitution, addition, and elimination, making it a versatile starting material for the synthesis of a wide range of organic compounds.
Used in Research and Development:
6-Bromoveratraldehyde is also utilized in research and development settings, where it can be employed to study the effects of structural modifications on the properties and reactivity of organic molecules. This knowledge can be applied to the design and synthesis of new compounds with specific applications in various industries, such as pharmaceuticals, materials science, and agrochemicals.

InChI:InChI=1/C9H9BrO3/c1-12-8-3-6(5-11)7(10)4-9(8)13-2/h3-5H,1-2H3

Upstream product

• 22608-87-3 2-amino-4,5-dimethoxybenzaldehyde 
• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 60632-40-8 6-bromovanillin 
• 77-78-1 dimethyl sulfate 
• 74-88-4 methyl iodide 
• 2973-59-3 2-bromoisovanillin 
• 7726-95-6 bromine 
• 64-19-7 acetic acid 
• 26829-91-4 3-bromo-2-formyl-5,6-dimethoxy-benzoic acid 
• 272766-46-8 1-allyl-2-bromo-4,5-dimethoxybenzene 
• 157430-04-1 2-(2-bromo-4,5-dimethoxyphenyl)-[1,3]dithiane 
• 54370-00-2 2-bromo-4,5-dimethoxybenzyl alcohol 
• 14140-15-9 4-(2-bromoethyl)phenol 
• 121-33-5 vanillin 

Downstream Products

• 857832-83-8 3-((Ξ)-2-bromo-4,5-dimethoxy-benzylidene)-5-(3,4-dimethoxy-phenyl)-3H-furan-2-one 
• 2973-59-3 2-bromoisovanillin 
• 6286-46-0 2-bromo-4,5-dimethoxybenzoic acid 
• 4815-99-0 2-bromo-4,5-dihydroxybenzoaldehyde 
• 60632-40-8 6-bromovanillin 
• 198204-67-0 2-bromo-4,5-dimethoxybenzaldehyde oxime 
• 109305-96-6 6-bromo-3,4-dimethoxy-2-nitrobenzaldehyde 
• 501914-86-9 2-bromo-4,5-dimethoxy-benzaldehyde-(2,4-dinitro-phenylhydrazone)- 
• 74753-40-5 (E)-3-(2-bromo-4,5-dimethoxyphenyl)-1-(3,4-dimethoxyphenyl)prop-2-en-1-one 
• 5293-52-7 6-bromo-3,4-dimethoxy-α-methylbenzyl alcohol 
• 74746-09-1 2-bromo-4,5,3',4',5'-pentamethoxychalcone 
• 63624-30-6 4,5-dimethoxy-2-(methylthio)benzaldehyde 
• 106412-23-1 2-(3-hydroxy-3-methyl-1-buten-1-yl)-4,5-dimethoxybenzaldehyde 
• 74746-11-5 2,2'-dibromo-4,4',5,5'-tetramethoxychalcone 

Relevant articles and documents

Copolymerization of an indazole ligand into the self-polymerization of dopamine for enhanced binding with metal ions

5,6-Dihydroxy-1H-indazole (DHI) is able to self-polymerize through the same mussel-inspired chemistry responsible for generating poly(dopamine) (PDA), demonstrating the potential to expand this class of catecholamine-exclusive chemistry onto heterocyclic catechol derivatives for the preparation of functional materials. Although DHI exhibits slower polymerization kinetics compared to dopamine, the two chemical species are compatibly polymerizable under the same reaction conditions and allow the preparation of copolymer coatings in different molar ratios. Of these copolymers, the 1:3-copolymer (DHI-to-dopamine ratio) has demonstrated adequate structural stability as a polymer coating. While PDA performs as an intact framework, the incorporated DHI enhances the colloidal stability and provides additional coordinating functionality through the pyrazole moieties. The 1:3-copolymer was fabricated into polymer capsules which exhibit negligible cytotoxicity towards murine dermal fibroblasts (L929) and enhanced binding behaviour towards copper(ii). This represents a new channel for fabricating cargo carriers for biomedical applications that involve the use of transition metal-based species.

Diphyllin and application thereof in preparation of medicine for preventing or treating diabetes mellitus

The invention belongs to the technical field of medicine, and particularly relates to diphyllin represented by a formula I and an application of the diphyllin in preparation of medicine for preventingor treating diabetes mellitus, and experiments prove that the compound can improve insulin sensitivity of mice and reduce blood sugar. The compound is expected to be developed into a medicine for preventing or treating diabetes.

COMPOUNDS FOR THE INHIBITION OF UNREGULATED CELL GROWTH

The present invention discloses compounds for inhibition of uncontrolled cell proliferation particularly cancer stem cells. Particularly, the invention relates to compounds of Formula I to XXII for the treatment of cancer.