53918-89-1

Basic information

• Product Name: 2,3-Dimethyl-7-methoxy-1H-indole
• Synonyms: 2,3-Dimethyl-7-methoxy-1H-indole;7-Methoxy-2,3-dimethyl-1H-indole
• CAS NO: 53918-89-1
• Molecular Formula: C11H13NO
• Molecular Weight: 175.23
• Mol File: 53918-89-1.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2,3-Dimethyl-7-methoxy-1H-indole(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-Dimethyl-7-methoxy-1H-indole(53918-89-1)
• EPA Substance Registry System: 2,3-Dimethyl-7-methoxy-1H-indole(53918-89-1)

Safety Data

• Hazardous Substances Data: 53918-89-1(Hazardous Substances Data)

Upstream product

• 90-04-0 2-methoxy-phenylamine 
• 513-85-9 2.3-butanediol 
• 78-93-3 butanone 
• 380383-87-9 N-(2-methoxy-phenyl)-hydrazinecarboxylic acid tert-butyl ester 
• 4091-39-8 3-chloro-2-butanone 
• 18312-46-4 (2-methoxyphenyl)hydrazine 

Relevant articles and documents

Improved indole syntheses from anilines and vicinal diols by cooperative catalysis of ruthenium complex and acid

By developing a new and efficient dinuclear catalyst [Ru(CO) 2(Xantphos)]2 [Xantphos = 4,5-bis(diphenylphosphino)-9,9- dimethyl-9H-xanthene], an improved synthesis of indole from vicinal diols and anilines by cooperative catalysis of ruthenium complex and p-TSA (para-toluenesufonic acid) has been demonstrated. The presented synthetic protocol allows assembling a wide range of products in an efficient manner. Comparing to the existed protocols, our indole syntheses can be achieved at lower reaction temperature, in shorter reaction time, and with improved substrate tolerance.

Expedient synthesis of indoles from N-Boc arylhydrazines

The readily available N-Boc arylhydrazines undergo efficient Fischer cyclizations to provide the indoles in good yields, when reacted with enolizable ketones.