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  • 539-21-9 Structure
  • Basic information

    1. Product Name: Ambazone
    2. Synonyms: ambazone;p-benzoquinone amidinohydrazone thiosemicarbazone;1,4-Benzoquinone guanylhydrazone thiosemicarbazone;Faringosept;Inversal;((4-oxo-2,5-cyclohexadien-1-ylidene)amino)-guanidin thiosemicarbazone;((4-oxo-2,5-cyclohexadien-1-ylidene)amino)guanidine thiosemicarbazone;1-amidinohydrazono-4-thiosemicarbazono-2,5-cyclohexadiene
    3. CAS NO:539-21-9
    4. Molecular Formula: C8H11N7S
    5. Molecular Weight: 237.28484
    6. EINECS: 208-713-0
    7. Product Categories: Amines;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds
    8. Mol File: 539-21-9.mol
    9. Article Data: 2
  • Chemical Properties

    1. Melting Point: 195°C (rough estimate)
    2. Boiling Point: 160°C (rough estimate)
    3. Flash Point: 233.2°C
    4. Appearance: /
    5. Density: 1.2732 (rough estimate)
    6. Vapor Pressure: 1.03E-08mmHg at 25°C
    7. Refractive Index: 1.5500 (estimate)
    8. Storage Temp.: Hygroscopic, Refrigerator, under inert atmosphere
    9. Solubility: DMSO (Slightly), Methanol (Slightly)
    10. Stability: Very Hygroscopic
    11. CAS DataBase Reference: Ambazone(CAS DataBase Reference)
    12. NIST Chemistry Reference: Ambazone(539-21-9)
    13. EPA Substance Registry System: Ambazone(539-21-9)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 539-21-9(Hazardous Substances Data)

539-21-9 Usage

Originator

Ambazone,Generic

Uses

Ambazone is a benzoquidine diimine derivative useful as animal growth substance.

Manufacturing Process

To a solution of 22.7 g of quinone monoguanylhydrazone nitrate in 250 ml water is added dropwise hot aqueous solution of 9.1 g thiosemicarbazide, then is added slowly a solution of 5 ml concentrated nitric acid in 10 ml of water. The mixture is stirred at 60°C for 1 hour. The product is dissolved in 1-1.2 L of water at 100°C. The solution is filtered and added to an aqueous ammonium solution. Blue residue of p-benzoquinone amidinohydrazone thiosemicarbazone is filtered and dried, melting point 188°C (decomp.).

Therapeutic Function

Antiseptic

Check Digit Verification of cas no

The CAS Registry Mumber 539-21-9 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,3 and 9 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 539-21:
(5*5)+(4*3)+(3*9)+(2*2)+(1*1)=69
69 % 10 = 9
So 539-21-9 is a valid CAS Registry Number.
InChI:InChI=1/C8H11N7S/c9-7(10)14-12-5-1-3-6(4-2-5)13-15-8(11)16/h1-4,12H,(H2,11,16)(H4,9,10,14)/b15-13+

539-21-9Downstream Products

539-21-9Relevant articles and documents

Kinetics of the transformation of dihydroambazone into ambazone in different solutions

Miosga,Roemer,Amlacher

, p. 41 - 42 (2007/10/02)

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