5338-65-8 Usage
Description
AI3-18274 is a chemical compound that has been identified as a potential inhibitor of the enzyme dihydropteroate synthase (DHPS), which is involved in the synthesis of folic acid in bacteria. Folic acid is essential for the production of DNA and RNA, and inhibiting DHPS can prevent the growth and reproduction of bacteria. AI3-18274 has been studied for its potential as an antibacterial agent, particularly against drug-resistant strains of bacteria. Research has shown that AI3-18274 has the ability to effectively inhibit DHPS and has the potential to be developed into a new class of antibiotics. Further research is needed to fully understand its mechanism of action and its potential as a therapeutic agent.
Uses
Used in Pharmaceutical Industry:
AI3-18274 is used as an antibacterial agent for its ability to inhibit the enzyme dihydropteroate synthase (DHPS), which is involved in the synthesis of folic acid in bacteria. This inhibition prevents the growth and reproduction of bacteria, making it a potential candidate for the development of a new class of antibiotics, particularly against drug-resistant strains.
Used in Research and Development:
AI3-18274 is used as a research compound for further studies to understand its mechanism of action and its potential as a therapeutic agent. This research can help in the development of new strategies to combat drug-resistant bacteria and improve the effectiveness of existing antibiotics.
Check Digit Verification of cas no
The CAS Registry Mumber 5338-65-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,3,3 and 8 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 5338-65:
(6*5)+(5*3)+(4*3)+(3*8)+(2*6)+(1*5)=98
98 % 10 = 8
So 5338-65-8 is a valid CAS Registry Number.
InChI:InChI=1/C12H23NO2/c1-2-3-4-5-6-7-12(14)13-8-10-15-11-9-13/h2-11H2,1H3
5338-65-8Relevant articles and documents
XtalFluor-E, an efficient coupling reagent for amidation of carboxylic acids
Orliac, Aurélie,Gomez Pardo, Domingo,Bombrun, Agnès,Cossy, Janine
supporting information, p. 902 - 905 (2013/03/29)
Amides were produced from carboxylic acids and amines by using XtalFluor-E as an activator. Even poorly reactive carboxylic acids can be transformed to amides. In addition, optically active amines and/or carboxylic acids were not epimerized/racemized during the process.
Direct dehydrogenative amide synthesis from alcohols and amines catalyzed by γ-alumina supported silver cluster
Shimizu, Ken-Ichi,Ohshima, Keiichiro,Satsuma, Atsushi
supporting information; experimental part, p. 9977 - 9980 (2010/04/03)
The heterogeneously catalyzed reaction of alcohols with amines to form amides and H2 using the easily prepared and inexpensive heterogeneous catalyst, Ag/Al2O3 has been reported. Aromatic and aliphatic amides are functiona
Process for the preparation of carboxylic acid amides by oxidation of aldehydes in the presence of amines
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Page 4-5, (2008/06/13)
Verfahren zur Herstellung von mono-, bi- oder/und polyfunktionellen Amiden der Formeln (Ia) oder/und (Ib),R1-CO-NR2R3R4R5N-CO-R6-CO- NR2R3aus Aldehyden und Aminen in Gegenwart eines übergangsmetallkatalysators und einem Oxidationsmittel.