53341-46-1 Usage
Description
(E)-3-(diMethylaMino)-2-(M-tolyloxy)acrylaldehyde, also known as DMAOTA, is a chemical compound with the molecular formula C12H15NO2. It is a yellow crystalline solid that is commonly used as an intermediate in the synthesis of dyes and pharmaceuticals. DMAOTA is also used as a reagent in organic synthesis and as a fluorescent probe for biological imaging. It is important to handle DMAOTA with care, as it is a potentially hazardous chemical that should be used in a well-ventilated area and with appropriate protective equipment. Additionally, DMAOTA has been identified as a potential skin and eye irritant, and exposure should be avoided.
Uses
Used in Dye Synthesis:
DMAOTA is used as an intermediate in the synthesis of dyes, contributing to the production of various colorants for different industries.
Used in Pharmaceutical Synthesis:
DMAOTA serves as an intermediate in the production of pharmaceuticals, playing a crucial role in the development of new drugs.
Used as a Reagent in Organic Synthesis:
DMAOTA is utilized as a reagent in organic synthesis, facilitating various chemical reactions and contributing to the creation of a range of organic compounds.
Used as a Fluorescent Probe in Biological Imaging:
DMAOTA is employed as a fluorescent probe for biological imaging, allowing for the visualization and study of biological processes at the molecular level.
Used in Chemical Research:
DMAOTA is used in chemical research to explore new reactions, mechanisms, and applications, furthering the understanding of organic chemistry and its potential uses in various fields.
Used in Safety and Hazard Assessment:
Due to its potential hazards, DMAOTA is also used in the assessment of safety and hazard protocols, ensuring that appropriate measures are taken to protect individuals and the environment from potential exposure.
Check Digit Verification of cas no
The CAS Registry Mumber 53341-46-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,3,3,4 and 1 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 53341-46:
(7*5)+(6*3)+(5*3)+(4*4)+(3*1)+(2*4)+(1*6)=101
101 % 10 = 1
So 53341-46-1 is a valid CAS Registry Number.
53341-46-1Relevant articles and documents
METHOD FOR PREPARING TOLIMIDONE ON LARGE SCALE
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Paragraph 19; 74-76, (2019/08/20)
The present disclosure relates to a method for preparing tolimidone on large scale with maintaining high purity and uniform particle size distribution, and more specifically, a method suitable for preparing tolimidone on industrially large scale by using
Bronchodilator and Antiulcer Phenoxypyrimidinones
Lipinski, C. A.,Stam, J. G.,Pereira, J. N.,Ackerman, N. R.,Hess, H.-J.
, p. 1026 - 1031 (2007/10/02)
Series of 5-phenoxy-2(1H)-pyrimidinones, 5-phenoxy-4(3H)-pyrimidinones, and related compounds were prepared in a follow-up of a lead prepared as a potential cyclic nucleotide regulating agent.Compounds were evaluated for bronchodilator activity in histamine-challenged guinea pigs and for antiulcer activity in a cold-restraint, stressed rat ulcer model.Bronchodilator activity comparable to, or greater than, that of theophylline was found in both the 2(1H)- and 4(3H)-pyrimidinone series and was most prominent in analogues containing either an electron-withdrawing or -donating substituent in the para position of the phenoxy ring.Significant antiulcer activity was observed only in the 2(1H)-pyrimidinone series among three closely related analogues.One of these, 5-(m-methylphenoxy)-2(1H)-pyrimidinone (3), exhibited more potent antiulcer effects than the clinically useful antiulcer agent carbenoxolone, without demonstrating bronchodilator activity.
