53121-41-8

Basic information

• Product Name: Dichlorophosphinic acid octyl ester
• Synonyms: Dichlorophosphinic acid octyl ester
• CAS NO: 53121-41-8
• Molecular Formula: C₈H₁₇Cl₂O₂P
• Molecular Weight: 247.1
• Mol File: 53121-41-8.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Dichlorophosphinic acid octyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Dichlorophosphinic acid octyl ester(53121-41-8)
• EPA Substance Registry System: Dichlorophosphinic acid octyl ester(53121-41-8)

Safety Data

• Hazardous Substances Data: 53121-41-8(Hazardous Substances Data)

Upstream product

• 111-87-5 octanol 
• 463-71-8 thiophosgene 
• 97-95-0 2-ethyl-1-butanol 

Downstream Products

• 29701-85-7 diphenyl-n-oct-1-ylphosphine oxide 
• 85357-57-9 (1-methylheptyl)diphenylphosphine oxide 
• 172693-83-3 1⁴-<4-phenyldiazenyl>-2,5,8,11-tetraoxa-1(1,2)-benzenacycloundecaphane 
• 172693-81-1 1⁴-<4-phenyldiazenyl>-2,5,8,11,14-pentaoxa-1(1,2)-benzenacyclotetradecaphane 
• 3991-73-9 monooctylphosphoric acid 
• 115-88-8 n-octyl diphenyl phosphate 
• 172693-82-2 1⁴-<4-phenyldiazenyl>-2,5,8,11-tetraoxa-1(1,2)-benzenacycloundecaphane 
• 172693-80-0 1⁴-<4-phenyldiazenyl>-2,5,8,11,14-pentaoxa-1(1,2)-benzenacyclotetradecaphane 
• 53255-89-3 octylphosphocholine 
• 20195-13-5 n-octyl diethyl phosphate 

Relevant articles and documents

Lipid-mimicking phosphorus-based glycosidase inactivators as pharmacological chaperones for the treatment of Gaucher's disease

Gaucher's disease, the most prevalent lysosomal storage disorder, is caused by missense mutation of the GBA gene, ultimately resulting in deficient GCase activity, hence the excessive build-up of cellular glucosylceramide. Among different therapeutic strategies, pharmacological chaperoning of mutant GCase represents an attractive approach that relies on small organic molecules acting as protein stabilizers. Herein, we expand upon a new class of transient GCase inactivators based on a reactive 2-deoxy-2-fluoro-β-d-glucoside tethered to an array of lipid-mimicking phosphorus-based aglycones, which not only improve the selectivity and inactivation efficiency, but also the stability of these compounds in aqueous media. This hypothesis was further validated with kinetic and cellular studies confirming restoration of catalytic activity in Gaucher cells after treatment with these pharmacological chaperones.

GELLED HYDROCARBONS FOR OILFIELD PROCESSES, PHOSPHATE ESTER COMPOUNDS USEFUL IN GELLATION OF HYDROCARBONS AND METHODS FOR PRODUCTION AND USE THEREOF

Phosphate esters useful for gelling hydrocarbons in combination with a metal source are disclosed along with methods of preparation of the phosphate esters. Fouling in oil refinery towers has been attributed due to distillation of impurities present in phosphate esters used to gel hydrocarbons for oil well fracturing. The improved method of preparation of the phosphate ester results in a product that substantially reduces or eliminates volatile phosphorus, which is phosphorus impurities that distill up to 250° C., and increases the high temperature viscosity of the hydrocarbon gels formed using the phosphate esters.

Synthesis of chlorothioformates from xanthates

The Vilsmeier reagent derived from N-formylmorpholine produces chlorothioformates from primary and secondary alkyl xanthates. The major side products are the corresponding alkyl chlorides. Secondary alkyl chlorothioformates give lower yields due to their instability. Treating xanthates with other common chlorinating agents (oxalyl chloride, thionyl chloride) gives only dialkyl thiodicarbonates. Georg Thieme Verlag Stuttgart.