525-01-9 Usage
Description
Linadryl is a combination of two active ingredients, diphenhydramine and zinc acetate, which is commonly used as an antihistamine and anti-itch medication. Diphenhydramine works by blocking the effects of histamine, a substance in the body that causes allergic symptoms, while zinc acetate acts as an astringent, helping to soothe and protect the skin. Together, these chemicals provide relief from symptoms such as itching, rashes, and insect bites.
Uses
Used in Pharmaceutical Industry:
Linadryl is used as an antihistamine and anti-itch medication for treating allergic symptoms such as itching, rashes, and insect bites. The combination of diphenhydramine and zinc acetate in Linadryl helps to block histamine effects and soothe the skin, providing relief from these symptoms.
Used in Dermatological Applications:
Linadryl is used as a topical treatment for skin conditions that cause itching and irritation. The diphenhydramine in Linadryl blocks the histamine responsible for allergic reactions, while the zinc acetate acts as an astringent to soothe and protect the skin, making it suitable for treating various skin conditions.
It is important to follow the instructions provided on the product packaging and consult a healthcare professional before using Linadryl to ensure safety and effectiveness. Linadryl is available in various forms such as lotions, creams, and ointments, allowing for easy application to the affected area.
Check Digit Verification of cas no
The CAS Registry Mumber 525-01-9 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,2 and 5 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 525-01:
(5*5)+(4*2)+(3*5)+(2*0)+(1*1)=49
49 % 10 = 9
So 525-01-9 is a valid CAS Registry Number.
InChI:InChI=1/C19H23NO2/c1-3-7-17(8-4-1)19(18-9-5-2-6-10-18)22-16-13-20-11-14-21-15-12-20/h1-10,19H,11-16H2
525-01-9Relevant articles and documents
Ruthenium Complex Catalyzed N-Heterocyclization. Syntheses of N-Substituted Piperidines, Morpholines, and Piperazines from Amines and 1,5-Diols
Tsuji, Yasushi,Huh, Keun-Tae,Ohsugi, Yukihiro,Watanabe, Yoshihisa
, p. 1365 - 1370 (2007/10/02)
1,5-Pentanediol reacts with aliphatic and aromatic primary amines in the presence of a ruthenium catalyst modified with phosphonic ligands to give N-substituted piperidines in fair to goods yields.The reactions were carried out at 150-180 deg C for 5 h in dioxane.The nature of the phosphorus ligands has a remarkable effect on the catalytic activity, For the reaction of aromatic amines, triphenylphosphine is effective, while for aliphatic amine more basic tributyl- or triethylphosphine is preferable.Amines also react with diethylene glycol and N-substituted diethanolamines in the presence of the ruthenium catalyst to give N-substituted morpholines and piperazines in good yields, respectively.