5216-31-9

Basic information

• Product Name: 4,4'-DIFLUORODIPHENYLACETYLENE
• Synonyms: 4,4'-DIFLUORODIPHENYLACETYLENE;1,2-Bis(4-fluorophenyl)ethyne
• CAS NO: 5216-31-9
• Molecular Formula: C₁₄H₈F₂
• Molecular Weight: 214.2101264
• Mol File: 5216-31-9.mol
• Article Data: 79

Chemical Properties

• Melting Point: 92-94 °C
• Boiling Point: 291.9±25.0 °C(Predicted)
• Appearance: /
• Density: 1.21±0.1 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 4,4'-DIFLUORODIPHENYLACETYLENE(CAS DataBase Reference)
• NIST Chemistry Reference: 4,4'-DIFLUORODIPHENYLACETYLENE(5216-31-9)
• EPA Substance Registry System: 4,4'-DIFLUORODIPHENYLACETYLENE(5216-31-9)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 5216-31-9(Hazardous Substances Data)

Usage

Description

4,4'-DIFLUORODIPHENYLACETYLENE, with the molecular formula C14H6F2, is a colorless solid chemical compound. It is insoluble in water but soluble in organic solvents, making it a versatile component in various applications within the fields of organic chemistry and materials science.

Uses

Used in Organic Synthesis:
4,4'-DIFLUORODIPHENYLACETYLENE is used as a building block in organic synthesis for its ability to form a variety of complex organic compounds, contributing to the development of new materials and chemical entities.
Used in Organic Electronic Materials Production:
In the industry of organic electronic materials, 4,4'-DIFLUORODIPHENYLACETYLENE is used as a key component in the production of OLEDs (organic light-emitting diodes) and OLED displays, due to its unique electronic properties that enhance the performance and efficiency of these devices.
Used in Biochemical and Medical Research:
4,4'-DIFLUORODIPHENYLACETYLENE serves as a fluorescent probe in biochemical and medical research, where its optical properties allow for the tracking and imaging of biological processes at the molecular level, aiding in the understanding of disease mechanisms and the development of therapeutic strategies.
Used in Polymer and Pharmaceutical Production:
4,4'-DIFLUORODIPHENYLACETYLENE is also utilized in the production of polymers and pharmaceuticals, where its chemical structure can be tailored to achieve specific properties and functions, such as improved drug delivery systems or advanced polymer materials with unique characteristics.

Upstream product

• 565-04-8 α,α,α',α'-tetrachloro-4,4'-difluoro-bibenzyl 
• 23349-10-2 4,4'-(2-bromoethene-1,1-diyl)bis(fluorobenzene) 
• 352-34-1 4-fluoro-1-iodobenzene 
• 95895-33-3 1-(bromoethynyl)-4-fluorobenzene 
• 706-06-9 3-(4-flurophenyl)prop-2-ynoic acid 
• 460-00-4 1-Bromo-4-fluorobenzene 
• 459-45-0 4-fluorobenzenediazonium tetrafluoroborate 
• 75-20-7 calcium carbide 
• 5963-39-3 hex-3-yne-1,6-dioic acid 
• 130995-12-9 1-(4-fluorophenyl)-2-trimethylsilylacetylene 
• 1066-54-2 trimethylsilylacetylene 
• 352-13-6 4-flourophenylmagnesium bromide 
• 471-25-0 Propiolic acid 
• 1675-57-6 diethynyldiphenylsilane 

Downstream Products

• 1092707-47-5 (η4-tetra(para-fluorophenyl)cyclobutadiene)(η5-carbomethoxycyclopentadienyl)cobalt 
• 1092707-34-0 (η5-cyclopentadienyl)(triphenylphosphine)-2,3,4,5-tetra(para-trifluorophenyl)cobaltacyclopentadiene 
• 1217677-84-3 4,4',4''-(4-phenylbut-1-en-3-yne-1,1,2-tryl)tris(fluorobenzene) 
• 1217677-82-1 4,4',4'',4'''-(but-1-en-3-yne-1,1,2,4-tetrayl)tetrakis(fluorobenzene) 
• 1255383-29-9 diethyl (2E,4Z)-4,5-bis(4-fluorophenyl)-2,4-octadienedioate 
• 1332835-92-3 C₂₁H₁₅F₂NO 
• 1332835-86-5 C₂₃H₁₇F₂NO₂ 
• 1393377-87-1 C₂₉H₁₆Br₂F₂O 
• 579-39-5 1,2-bis(4-fluorophenyl)ethane-1,2-dione 
• 1223047-89-9 (Z)-1-(2-phenyl-2-p-fluorophenylvinyl)-4-fluoro benzene 
• 1449590-13-9 (Z)-4,4'-(1-p-tolylethene-1,2-diyl)bis(fluorobenzene) 
• 628320-79-6 2,3-bis(4-fluorophenyl)-1H-indole 
• 1601494-63-6 3,4-bis(4-fluorophenyl)-2-(4-methoxyphenyl)-6-methyl-1-methylene-1,2-dihydroisoquinoline 
• 1609133-00-7 C₃₇H₂₀F₄O₃ 

Relevant articles and documents

Nickel-Catalyzed Decarbonylative Cycloaddition of Benzofuran-2,3-diones with Alkynes to Flavones

Using dppe as the ligand, the Nickel-catalyzed decarbonylative cycloaddition of benzofuran-2,3-diones with alkynes was established, and a variety of functional flavones were synthesized in 65–99% yields. Terminal alkynes with substituted phenyl groups and internal alkynes such as aryl acyl acetylenes and diphenylacetylenes are suitable for this reaction. The effects of bases on the reactions of different types of alkyne substrates were also investigated and discussed. (Figure presented.).

Selective Synthesis of Non-Aromatic Five-Membered Sulfur Heterocycles from Alkynes by using a Proton Acid/N-Chlorophthalimide System

A multicomponent strategy to achieve two different regioselectivities from alkynes, isothiocyanates and H2O with a proton acid/N-chlorophthalimide (NCPI) system is described to selectively obtain non-aromatic five-membered sulfur heterocycles (1,3-oxathiol-2-imines/thiazol-2(3H)-one derivatives) through multiple bond formations. The process features readily available starting materials, mild reaction conditions, broad substrate scope, good functional-group tolerance, high regio- and chemo- selectivities, gram-scale synthesis and late-stage modifications. Mechanistic studies support the proposal that the transformation process includes a combination of H2O and isothiocyanate, free-radical formation, carbonation and intramolecular cyclization to give the products. Furthermore, the 1,3-oxathiol-2-imine derivatives possess unique fluorescence characteristics and can be used as Pd2+ sensors with a “turn-off” response, demonstrating potential applications in environmental and biological fields.

Synthesis of Bidentate Nitrogen Ligands by Rh-Catalyzed C-H Annulation and Their Application to Pd-Catalyzed Aerobic C-H Alkenylation

A new class of bidentate ligands was prepared by a modular approach involving Rh-catalyzed C-H annulation reactions. The resulting conformationally constrained ligands enabled the Pd-catalyzed C-H alkenylation at electron-rich and sterically less hindered positions of electron-rich arenes while promoting the facile oxidation of Pd(0) intermediates by oxygen. This newly introduced ligand class is complementary to the ligands developed for Pd-catalyzed oxidative reactions and may find broad application in transition-metal-catalyzed reactions.