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519-12-0

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519-12-0 Usage

Description

Setoclavine is an ergot alkaloid derived from the mycelia of Claviceps purpurea. It forms colorless prisms when crystallized from Me2CO or MeOH and exhibits dextrorotatory properties with specific optical rotations in different solvents. The ultraviolet spectrum in EtOH shows two absorption maxima at 243 and 313 mJ. The alkaloid can form crystalline salts with mineral acids, such as hydrochloride and nitrate, both with melting points above 300°C.

Uses

1. Used in Pharmaceutical Industry:
Setoclavine is used as an active pharmaceutical ingredient for its various biological activities. Its alkaloid nature allows it to form salts with mineral acids, which can be utilized in the development of medications.
2. Used in Research and Development:
Setoclavine's unique properties, such as its optical rotation and ultraviolet spectrum, make it a valuable compound for research purposes. It can be used in the study of ergot alkaloids, their interactions with biopolymers, and their potential applications in medicine.
3. Used in Drug Delivery Systems:
Similar to gallotannin, setoclavine can be incorporated into drug delivery systems to improve its bioavailability and therapeutic outcomes. The development of novel drug delivery systems, such as organic and metallic nanoparticles, can enhance the efficacy of setoclavine in targeted applications.
4. Used in Chemical Synthesis:
Setoclavine's ability to form crystalline salts with mineral acids can be exploited in chemical synthesis for the development of new compounds with potential applications in various industries, including pharmaceuticals, agrochemicals, and materials science.

References

Hofmann et al., Helv. Chim. Acta, 40, 1358 (1957)

Check Digit Verification of cas no

The CAS Registry Mumber 519-12-0 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,1 and 9 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 519-12:
(5*5)+(4*1)+(3*9)+(2*1)+(1*2)=60
60 % 10 = 0
So 519-12-0 is a valid CAS Registry Number.

519-12-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name (+)-setoclavine

1.2 Other means of identification

Product number -
Other names 6,8-dimethyl-9,10-didehydro-ergolin-8-ol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:519-12-0 SDS

519-12-0Downstream Products

519-12-0Relevant articles and documents

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Brack et al.

, p. 276,279 (1962)

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Ergoline derivatives. XIV. Synthesis of clavine alkaloids

Bernadi,Gandini,Temperilli

, p. 3447 - 3450 (2007/10/04)

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