517-97-5

Basic information

• Product Name: Tsuduranine
• Synonyms: Tsuduranine;(6aR)-5,6,6a,7-Tetrahydro-1,2-dimethoxy-4H-dibenzo[de,g]quinolin-10-ol;Tuduranine
• CAS NO: 517-97-5
• Molecular Formula: C18H19NO3
• Molecular Weight: 297.34836
• Mol File: 517-97-5.mol
• Article Data: 2

Chemical Properties

• Melting Point: about 125° (softens at 105°), or 204°
• Boiling Point: 438.86°C (rough estimate)
• Flash Point: 254.4°C
• Appearance: /
• Density: 1.1823 (rough estimate)
• Vapor Pressure: 1.67E-10mmHg at 25°C
• Refractive Index: 1.5100 (estimate)
• PKA: 9.76±0.20(Predicted)
• CAS DataBase Reference: Tsuduranine(CAS DataBase Reference)
• NIST Chemistry Reference: Tsuduranine(517-97-5)
• EPA Substance Registry System: Tsuduranine(517-97-5)

Safety Data

• Hazardous Substances Data: 517-97-5(Hazardous Substances Data)

Usage

Description

Tsuduranine is an aporphine alkaloid that is found alongside sinomenine in Sinomenium acutum Rehd. et Wils. It was first isolated by Goto from the mother liquors following the removal of the former base. This alkaloid is crystalline in nature, with a melting point of 125°C when crystallized from ethanol. Tsuduranine is laevorotatory, soluble in most organic solvents and dilute alkalies, and has a series of derivatives due to the presence of a phenolic hydroxyl group and an imino group.

Uses

1. Used in Pharmaceutical Industry:
Tsuduranine is used as a pharmaceutical compound for its potential therapeutic applications. The expression is: "Tsuduranine is used as a pharmaceutical compound for its potential therapeutic applications."
2. Used in Chemical Research:
Tsuduranine is used as a subject of study in chemical research due to its unique properties and the variety of derivatives it can form. The expression is: "Tsuduranine is used as a subject of study in chemical research for its unique properties and the variety of derivatives it can form."
3. Used in Organic Synthesis:
Tsuduranine can be used in organic synthesis to create various compounds and derivatives, contributing to the development of new pharmaceuticals and chemicals. The expression is: "Tsuduranine is used in organic synthesis for the creation of various compounds and derivatives."

References

Goto.,Annalen, 521,175(1935) Goto, Shishido., ibid, 539,262 (1939) Goto, Shishido., Proc. Imp. Acad. Tokyo, 15, 8 (1939) Goto, Yamamato., ibid, 29, 513 (1953)

InChI:InChI=1/C18H19NO3/c1-21-15-8-11-5-6-19-14-7-10-3-4-12(20)9-13(10)17(16(11)14)18(15)22-2/h3-4,8-9,14,19-20H,5-7H2,1-2H3/t14-/m1/s1

Upstream product

• 20698-14-0 (R)-(-)-stepharine 

Relevant articles and documents

Studies on the alkaloids of menispermaceous plants. CCXXVII. Alkaloids of Stephania rotunda Loureiro. (suppl. 2)

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