517-92-0 Usage
Description
1,8-dihydroxy-2,4,5,7-tetranitroanthraquinone is a chemical compound belonging to the anthraquinone family, characterized by its yellow-to-orange crystalline powder form.
Uses
Used in Propellant Industry:
1,8-dihydroxy-2,4,5,7-tetranitroanthraquinone is used as a high-energy oxidizer for enhancing the performance of solid rocket propellants, contributing to their combustion efficiency and energy output.
Used in Dye Industry:
1,8-dihydroxy-2,4,5,7-tetranitroanthraquinone serves as a red dye, utilized in various applications that require coloration, such as textiles, inks, and pigments.
Used in Chemical Synthesis:
1,8-dihydroxy-2,4,5,7-tetranitroanthraquinone is employed as a precursor in the synthesis of other organic compounds, facilitating the creation of new chemical entities for various industrial applications.
Safety Note:
Due to its explosive nature and potential toxicity, 1,8-dihydroxy-2,4,5,7-tetranitroanthraquinone must be handled and stored with extreme caution, adhering to stringent safety regulations to prevent accidents and health hazards.
Check Digit Verification of cas no
The CAS Registry Mumber 517-92-0 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,1 and 7 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 517-92:
(5*5)+(4*1)+(3*7)+(2*9)+(1*2)=70
70 % 10 = 0
So 517-92-0 is a valid CAS Registry Number.
InChI:InChI=1/C14H4N4O12/c19-11-5(17(27)28)1-3(15(23)24)7-9(11)14(22)10-8(13(7)21)4(16(25)26)2-6(12(10)20)18(29)30/h1-2,19-20H
517-92-0Relevant articles and documents
Synthesis and biological evaluation of new derivatives of emodin
Teich, Lars,Daub, Katja Scarlett,Krügel, Vera,Nissler, Ludwig,Gebhardt, Rolf,Eger, Kurt
, p. 5961 - 5971 (2004)
Synthesis and characterization of new emodin derivatives. Cytostatic potential and binding to multi-drug-resistance transporters were evaluated. Drugs containing an anthraquinone moiety such as daunorubicin (Daunoblastin) and mitoxantrone (Onkotrone) constitute some of the most powerful cytostatics. They suppress tumor growth mainly by intercalation into DNA and inhibition of topoisomerase II, and are suspected to generate free radicals leading to DNA strand scission. We established a novel strategy for obtaining new highly functionalized derivatives of emodin (1,3,8-trihydroxy-6- methyl-anthraquinone). Using emodin, DIB, and an appropriate amine as starting materials, we obtained a wide range of emodin-related structures by one-pot synthesis. Several of these derivatives showed stronger cytotoxic and cytostatic activity than emodin. In particular, compound 6 was highly effective on the HepG2 tumor cell line, but did not show any cytotoxicity on normal hepatocytes. In addition to this favorable feature, compound 6 revealed interesting binding properties to a recombinant fragment of the multi-drug-resistance transporter, pgp, and reversed the multi-drug-resistance phenotype of H4-II-E cells, thus making this compound a promising potential anti-tumor drug.