514-73-8 Usage
Description
3,3'-DIETHYLTHIADICARBOCYANINE IODIDE, also known as DTDCi, is a green crystalline powder with needle-like crystals. It is a versatile compound that has found applications in various fields due to its unique properties.
Uses
Used in Fluorescent Applications:
3,3'-DIETHYLTHIADICARBOCYANINE IODIDE is used as a fluorescent contrast agent in three-dimensional fluorescence lifetime tomography for its ability to enhance the visualization of biological structures and processes.
Used in Genetic Screening:
DDTDCi is employed as a dye for rapid genetic screening, facilitating the identification and analysis of genetic material in a timely and efficient manner.
Used in Photographic Industry:
As a sensitizer for photographic emulsions, 3,3'-DIETHYLTHIADICARBOCYANINE IODIDE improves the sensitivity and quality of photographic films, making it an essential component in the production of high-quality images.
Used in Veterinary Medicine:
3,3'-DIETHYLTHIADICARBOCYANINE IODIDE is used as a veterinary anthelmintic, helping to treat and prevent parasitic infections in animals.
Used in Insecticides:
It is also utilized as an active ingredient in insecticides, providing an effective means of controlling and eliminating insect pests.
Originator
Delvex,Lilly,US,1958
Manufacturing Process
3.05 g of 1-methylbenzthiazole ethiodide, 1.11 g of β-ethyl thio acrolein
diethyl acetal and 15 cc of pyridine were mixed and boiled gently under reflux
for 15 minutes. The reaction mixture was then poured into an aqueous
solution of potassium iodide. The dye was precipitated and was filtered off,
and washed with ethyl alcohol and ether. Recrystallization from methyl alcohol
solution yielded the dye as green needles. Melting point 248°C with
decomposition.
Therapeutic Function
Anthelmintic
World Health Organization (WHO)
Dithiazanine iodide, an anthelminthic, was introduced in 1959 for
the treatment of strongyloid worms and whipworms. Between 1961 and 1964 its
use was associated with eight fatal cases of severe acidosis and shock. Although
the drug is not significantly absorbed from the gut, in normal circumstances it was
assumed that these fatalities were due to atypically high uptake from inflamed
intestinal mucosa. Dithiazanine iodide has been superseded by safer and more
effective drugs; however, it may remain available in some countries.
Reactivity Profile
An amine, organosulfide. Organosulfides are incompatible with acids, diazo and azo compounds, halocarbons, isocyanates, aldehydes, alkali metals, nitrides, hydrides, and other strong reducing agents. Reactions with these materials generate heat and in many cases hydrogen gas. Many of these compounds may liberate hydrogen sulfide upon decomposition or reaction with an acid. Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.
Health Hazard
Highly toxic by mouth. (Non-Specific -- Pesticide, Solid, n.o.s.) Poisonous if swallowed, or if dust is inhaled.
Fire Hazard
When heated to decomposition, 3,3'-DIETHYLTHIADICARBOCYANINE IODIDE emits toxic fumes of iodine, sulfur oxides, and nitrogen oxides.
Safety Profile
Poison by ingestion,
intraperitoneal, and intravenous routes.
When heated to decomposition it emits very
toxic fumes of I-, SOx, and NOx. See also
IODIDES.
Check Digit Verification of cas no
The CAS Registry Mumber 514-73-8 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,1 and 4 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 514-73:
(5*5)+(4*1)+(3*4)+(2*7)+(1*3)=58
58 % 10 = 8
So 514-73-8 is a valid CAS Registry Number.
InChI:InChI=1/C10H16O/c1-7(2)8-4-5-10(3)9(6-8)11-10/h8-9H,1,4-6H2,2-3H3/t8-,9?,10?/m0/s1
514-73-8Relevant articles and documents
REACTIONS OF POLYMETHINE DYES. I. SYNTHESIS OF THE PSEUDOBASES OF POLYMETHINE DYES AND THEIR TRANSFORMATIONS
Vompe, A. F.,Ivanova, L. V.,Meskhi, L. M.,Monich, N. V.,Raikhina, R. D.
, p. 529 - 537 (2007/10/02)
Nonsalt-like benzene-soluble pseudobases are formed in the reaction of polymethine dyes with sodium alcoholates.The presence of ionized and un-ionized forms of the pseudobases was established by electronic absorption spectra in aprotic solvents.Solutions of these compounds in alcohols only contain the ionized forms; the unionized form predominates in benzene solutions.The action of various acids on the pseudobases leads to the production of polymethine dyes with the respective anions.
