504434-09-7

Basic information

• Product Name: 1H-pyrrole-2-carboxylic acid 3-fluoro-benzylamide
• Synonyms: 1H-pyrrole-2-carboxylic acid 3-fluoro-benzylamide
• CAS NO: 504434-09-7
• Molecular Weight: 218.231
• Mol File: 504434-09-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1H-pyrrole-2-carboxylic acid 3-fluoro-benzylamide(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-pyrrole-2-carboxylic acid 3-fluoro-benzylamide(504434-09-7)
• EPA Substance Registry System: 1H-pyrrole-2-carboxylic acid 3-fluoro-benzylamide(504434-09-7)

Safety Data

• Hazardous Substances Data: 504434-09-7(Hazardous Substances Data)

Upstream product

• 35302-72-8 pyrrol-2-yl trichloromethyl ketone 
• 100-82-3 (3-fluorophenyl)methanamine 

Downstream Products

• 504434-10-0 1-methyl-1H-pyrrole-2-carboxylic acid 3-fluoro-benzylamide 

Relevant articles and documents

Simple, potent, and selective pyrrole inhibitors of monoamine oxidase types A and B

N-Benzyl- and N-propargyl-1H-pyrrole-2-carboxyamides and some related methylenamines were synthesized and tested for their monoamine oxidase types A and B inhibitory activity. 2-(N-Methyl-N-propargylaminomethyl)-1H-pyrrole (24) was the most potent MAO-A inhibitor of the series [Ki(MAO-A) = 0.0054 μM], but it was not selective. Inhibitors N-4-fluorobenzyl-1H-pyrrole-2-carboxamide (12) and N-cyclohexylmethyl-1H-pyrrole-2-carboxamide (25) showed the highest MAO-A selectivity indexes (SI) corresponding to 2025 and > 2500, respectively, while 2-(N-methyl-N-benzylaminomethyl)-1H-pyrrole (21) was the most selective MAO-B inhibitor, having an SI of 0.0057.