502-97-6 Usage
Description
1,4-Dioxane-2,5-dione, also known as Glycolide, is a cyclic dimer of α-hydroxy acid derived from the dimerization of glycolic acid. It is a low toxic synthetic biodegradable polymer with a melting point of 82-86°C and a purity of 99.5% or higher. Its chemical structure and properties make it suitable for various applications, particularly in the medical field.
Uses
Used in Medical Applications:
1,4-Dioxane-2,5-dione is used as a key component in the fabrication of artificial blood vessels due to its biodegradable and biocompatible nature. It provides the necessary structural integrity and flexibility required for such applications.
Used in Polymer Synthesis:
In the field of polymer chemistry, 1,4-Dioxane-2,5-dione is used as a monomer for the formation of aliphatic polyesters, specifically poly(glycolide), through ring-opening polymerization. This highly crystalline polymer finds applications in various industries, including medical, pharmaceutical, and environmental sectors.
Used in Drug Delivery Systems:
1,4-Dioxane-2,5-dione is also utilized in the development of drug delivery systems, where its biodegradable properties allow for controlled release of therapeutic agents, enhancing their efficacy and reducing side effects.
Used in Tissue Engineering:
In the field of tissue engineering, 1,4-Dioxane-2,5-dione is employed as a scaffold material for the growth and regeneration of various tissues, such as bone, cartilage, and skin, due to its biocompatibility and ability to support cell adhesion and proliferation.
Used in Environmental Applications:
1,4-Dioxane-2,5-dione is used in the development of biodegradable plastics and other materials, which can help reduce the environmental impact of non-degradable synthetic materials. Its biodegradable nature makes it an attractive option for sustainable product development.
Flammability and Explosibility
Notclassified
Check Digit Verification of cas no
The CAS Registry Mumber 502-97-6 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,0 and 2 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 502-97:
(5*5)+(4*0)+(3*2)+(2*9)+(1*7)=56
56 % 10 = 6
So 502-97-6 is a valid CAS Registry Number.
InChI:InChI=1/C4H4O4/c5-3-1-7-4(6)2-8-3/h1-2H2
502-97-6Relevant articles and documents
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Andreas et al.
, p. 141,143 (1962)
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PROCESS FOR PREPARING GLYCOLIDE
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Page/Page column 14-17, (2020/07/05)
According to the present invention a process is provided for producing glycolide which comprises contacting glycolaldehyde dimer with an oxidizing agent to produce a glycolide product.Preferably, the process is carried out in an aprotic environment, such as in a reaction mixture comprising the glycolaldehyde dimer, the oxidizing agent, the glycolide product and an aprotic solvent.
METHOD FOR PRODUCING GLYCOLIDE
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Paragraph 0083-0093, (2019/10/30)
PROBLEM TO BE SOLVED: To provide a method for producing glycolides, with which glycolides can be produced more rapidly. SOLUTION: The method for producing glycolides comprises: an oligomer preparation step for obtaining a glycolic acid oligomer by heating an aqueous glycolic acid solution and by the dehydropolycondensation of the glycolic acid contained in the aqueous glycolic acid solution; and a depolymerization step for obtaining a glycolide by depolymerization of the glycolic acid oligomer in the presence of divalent iron ions. SELECTED DRAWING: None COPYRIGHT: (C)2019,JPOandINPIT
