49772-93-2

Basic information

• Product Name: 5-benzyloxy-3-phenyl-1,2,4-oxadiazole
• Synonyms: 5-benzyloxy-3-phenyl-1,2,4-oxadiazole
• CAS NO: 49772-93-2
• Molecular Weight: 252.272
• Mol File: 49772-93-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 5-benzyloxy-3-phenyl-1,2,4-oxadiazole(CAS DataBase Reference)
• NIST Chemistry Reference: 5-benzyloxy-3-phenyl-1,2,4-oxadiazole(49772-93-2)
• EPA Substance Registry System: 5-benzyloxy-3-phenyl-1,2,4-oxadiazole(49772-93-2)

Safety Data

• Hazardous Substances Data: 49772-93-2(Hazardous Substances Data)

Upstream product

• 827-44-1 5-chloro-3-phenyl-1,2,4-oxadiazole 
• 100-51-6 benzyl alcohol 

Relevant articles and documents

Rh(II)-Catalyzed Transannulation of 1,2,4-Oxadiazole Derivatives with 1-Sulfonyl-1,2,3-triazoles: Regioselective Synthesis of 5-Sulfonamidoimidazoles

An effective method for the synthesis of fully substituted 5-sulfonamidoimidazoles by Rh(II)-catalyzed transannulation of 1,2,4-oxadiazole derivatives with N-sulfonyl-1,2,3-triazoles is reported. The reaction works well with both aromatic 1,2,4-oxadiazoles and 1,2,4-oxadiazol-5-ones providing a flexible approach to N-(alkoxy/amino)carbonyl- and N-alkyl-substituted imidazoles. Both the disclosed reactions are completely regioselective and provide the first examples of a carbenoid-mediated transformation of N,N,O-heterocycles.