4878-14-2

Basic information

• Product Name: 2-(3-Chloro-phenoxy)-propionyl chloride
• Synonyms: 2-(3-Chloro-phenoxy)-propionyl chloride
• CAS NO: 4878-14-2
• Molecular Weight: 219.067
• Mol File: 4878-14-2.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2-(3-Chloro-phenoxy)-propionyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3-Chloro-phenoxy)-propionyl chloride(4878-14-2)
• EPA Substance Registry System: 2-(3-Chloro-phenoxy)-propionyl chloride(4878-14-2)

Safety Data

• Hazardous Substances Data: 4878-14-2(Hazardous Substances Data)

Upstream product

• 101-10-0 2-(3-chlorophenoxy)propionic acid 
• 108-43-0 3-monochlorophenol 

Downstream Products

• 122674-94-6 (S)-methyl 2-(3-chlorophenoxy) propionate 
• 140146-14-1 (R)-methyl 2-(3-chlorophenoxy) propionate 
• 101-10-0 (S)-2-(3-chlorophenoxy) propanoic acid 
• 101-10-0 (R)-(+)-2-(3-chlorophenoxy)propionic acid 
• 122623-81-8 methyl 2-(3-chlorophenoxy)propionate 

Relevant articles and documents

Discovery and optimization of (R)-prolinol-derived agonists of the Growth Hormone Secretagogue receptor (GHSR)

The discovery and optimization of a novel series of prolinol-derived GHSR agonists is described. This series emerged from a 11,520-member solid-phase library targeting the GPCR protein superfamily, and the rapid optimization of low micromolar hits into single-digit nanomolar leads can be attributed to the solid-phase synthesis of matrix libraries, which revealed multiple non-additive structure-activity relationships. In addition, the separation of potent diastereomers highlighted the influence of the α-methyl stereochemistry of the phenoxyacetamide sidechain on GHSR activity.

Biological Evaluation of some New Nitrophenoxy/Halophenoxyaeetyl/Propionyl-2-mercaptobenzothiazoles

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