475272-54-9 Usage
General Description
(S)-1-N-Boc-3-isopropylpiperazine is a chemical compound that belongs to the class of piperazine derivatives. It is commonly used as a building block in organic synthesis and medicinal chemistry. (S)-1-N-Boc-3-isopropylpiperazine is characterized by its N-Boc-protected piperazine ring with an isopropyl group attached to the nitrogen atom. The presence of the Boc protecting group makes (S)-1-N-Boc-3-isopropylpiperazine a versatile intermediate for the synthesis of complex organic molecules and pharmaceuticals. It is also utilized in the development of novel drug candidates and as a key ingredient in the preparation of various pharmaceutical products. Additionally, this compound has potential bioactivity and may exhibit pharmacological effects, making it a valuable tool in chemical and pharmaceutical research.
Check Digit Verification of cas no
The CAS Registry Mumber 475272-54-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,7,5,2,7 and 2 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 475272-54:
(8*4)+(7*7)+(6*5)+(5*2)+(4*7)+(3*2)+(2*5)+(1*4)=169
169 % 10 = 9
So 475272-54-9 is a valid CAS Registry Number.
InChI:InChI=1/C12H24N2O2/c1-9(2)10-8-14(7-6-13-10)11(15)16-12(3,4)5/h9-10,13H,6-8H2,1-5H3/t10-/m0/s1
475272-54-9Relevant articles and documents
Expedite protocol for construction of chiral regioselectively N-protected monosubstituted piperazine, 1,4-diazepane, and 1,4-diazocane building blocks
Crestey, Francois,Witt, Matthias,Jaroszewski, Jerzy W.,Franzyk, Henrik
supporting information; experimental part, p. 5652 - 5655 (2009/12/08)
(Chemical Equation Presented) This paper describes the first study of solution-phase synthesis of chiral monosubstituted piperazine building blocks from nosylamide-activated aziridines. The protocol, involving aminolysis of the starting aziridines with ω-amino alcohols and subsequent Fukuyama-Mitsunobu cyclization, offers the advantage of mild conditions as well as short reaction times, and it leads to optically pure N-Boc- or N-Ns-protected piperazines. This four-step sequence, requiring only a single final chromatographic purification, was extended to include novel diazepane and diazocane derivatives.
