4741-73-5

Basic information

• Product Name: Benzene, 1,1'-(1,3-propanediyl)bis[4-methoxy-
• CAS NO: 4741-73-5
• Molecular Formula: C17H20O2
• Molecular Weight: 256.345
• Mol File: 4741-73-5.mol
• Article Data: 12

Chemical Properties

• CAS DataBase Reference: Benzene, 1,1'-(1,3-propanediyl)bis[4-methoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1,1'-(1,3-propanediyl)bis[4-methoxy-(4741-73-5)
• EPA Substance Registry System: Benzene, 1,1'-(1,3-propanediyl)bis[4-methoxy-(4741-73-5)

Safety Data

• Hazardous Substances Data: 4741-73-5(Hazardous Substances Data)

Upstream product

• 2373-89-9 4,4'-dimethoxychalcone 
• 29903-09-1 1,3-bis(4-methoxyphenyl)acetone 
• 104-92-7 1-bromo-4-methoxy-benzene 
• 109-64-8 1,3-dibromo-propane 
• 13139-86-1 4-methoxyphenyl magnesium bromide 
• 13677-46-8 1,3-bis(4-methoxyphenyl)prop-2-en-1-ol 
• 140-67-0 Estragole 
• 4181-97-9 phenyl 4-methoxybenzoate 
• 374754-93-5 (9-BBN)(CH₂)3(p-anisyl) 
• 97-93-8 triethylaluminum 
• 100-06-1 1-(4-methoxyphenyl)ethanone 
• 123-11-5 4-methoxy-benzaldehyde 
• 34414-53-4 1,3-bis(4-methoxyphenyl)prop-1-ene 
• 702-23-8 2-(4-Methoxyphenyl)ethanol 

Downstream Products

• 2549-50-0 4,4′-(propane-1,3-diyl)diphenol 
• 136559-18-7 1,3-bis(3-acetyl-4-methoxyphenyl)propane 
• 1426234-52-7 1,3-bis(4-(prop-1-en-1-yloxy)phenyl)propane 
• 1426234-54-9 1-(2,2-diethyl-4-methylcyclobutoxy)-4-(3-(4-(prop-1-en-1-yloxy)-phenyl)propyl)benzene 
• 1426234-56-1 1,3-bis(4-(2,2-diethyl-4-methylcyclobutoxy)phenyl)propane 
• 136577-65-6 1,3-bis<3-(1-hydroxyethyl)-4-methoxyphenyl>propane 
• 136559-24-5 1,3-bis(3-vinyl-4-methoxyphenyl)propane 
• 29668-20-0 1,3-Bis-(3-acetyl-4-hydroxyphenyl)-propan 

Relevant articles and documents

NHC-Iridium-Catalyzed Deoxygenative Coupling of Primary Alcohols Producing Alkanes Directly: Synergistic Hydrogenation with Sodium Formate Generated in Situ

The direct conversion of alcohols into long-chain alkanes is an attractive but extremely challenging approach for biomass upgrading. Here, we describe the highly selective deoxygenative coupling of aryl ethanols with primary alcohols to produce alkanes, using a bis-N-heterocyclic carbene iridium (bis-NHC-Ir) complex as the catalyst. Up to quantitative yields and selectivity with a broad substrate scope are attained in both homo- and cross-coupling reactions. Mechanistic studies reveal that the further synergistic hydrogenation of the alkene intermediates by the formate generated in situ in the presence of bis-NHC-Ir is crucial for alkane production.

Direct α-Benzylation of Methyl Enol Ethers with Activated Benzyl Alcohols: Its Rearrangement and Access to (±)-Tetrahydronyasol, Propterol A, and 1,3-Diarylpropane

Herein, we report a one-pot Lewis acid mediated synthesis of bi- and triarylpropanal derivatives and their corresponding isomeric ketones from aromatic enol ethers. This transformation takes place via nucleophilic attack of enol ethers to electron-rich be

Ligand-Controlled Chemoselective C(acyl)-O Bond vs C(aryl)-C Bond Activation of Aromatic Esters in Nickel Catalyzed C(sp2)-C(sp3) Cross-Couplings

A ligand-controlled and site-selective nickel catalyzed Suzuki-Miyaura cross-coupling reaction with aromatic esters and alkyl organoboron reagents as coupling partners was developed. This methodology provides a facile route for C(sp2)-C(sp3) bond formation in a straightforward fashion by successful suppression of the undesired β-hydride elimination process. By simply switching the phosphorus ligand, the ester substrates are converted into the alkylated arenes and ketone products, respectively. The utility of this newly developed protocol was demonstrated by its wide substrate scope, broad functional group tolerance and application in the synthesis of key intermediates for the synthesis of bioactive compounds. DFT studies on the oxidative addition step helped rationalizing this intriguing reaction chemoselectivity: whereas nickel complexes with bidentate ligands favor the C(aryl)-C bond cleavage in the oxidative addition step leading to the alkylated product via a decarbonylative process, nickel complexes with monodentate phosphorus ligands favor activation of the C(acyl)-O bond, which later generates the ketone product.