466639-53-2

Basic information

• Product Name: 2-bromo-1-iodo-4-methoxybenzene
• Synonyms: 2-bromo-1-iodo-4-methoxybenzene;2-Bromo-1-iodo-4-methoxybenzene, 3-Bromo-4-iodophenyl methyl ether;3-Bromo-4-iodoanisole 97%;3-Bromo-4-iodoanisole;3-Bromo-4-iodoanisole97%
• CAS NO: 466639-53-2
• Molecular Formula: C₇H₆BrIO
• Molecular Weight: 312.93041
• Mol File: 466639-53-2.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 284.87°C at 760 mmHg
• Flash Point: 126.085°C
• Appearance: /
• Density: 2.063g/cm³
• Vapor Pressure: 0.005mmHg at 25°C
• Refractive Index: 1.624
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• CAS DataBase Reference: 2-bromo-1-iodo-4-methoxybenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 2-bromo-1-iodo-4-methoxybenzene(466639-53-2)
• EPA Substance Registry System: 2-bromo-1-iodo-4-methoxybenzene(466639-53-2)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 466639-53-2(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
2-Bromo-1-iodo-4-methoxybenzene is used as an intermediate in organic synthesis for the construction of complex organic molecules. Its presence of both a bromine and an iodine atom makes it a valuable compound for this application.
Used in Scientific Research:
2-Bromo-1-iodo-4-methoxybenzene is used as a research compound in various scientific applications, contributing to the development of new chemical processes and understanding of molecular interactions.
Used in Controlled Laboratory Settings:
Due to its potential reactivity and the need for further exploration of its physical characteristics and safety profile, 2-Bromo-1-iodo-4-methoxybenzene is primarily used in controlled laboratory or industrial settings to ensure safety and proper handling.

InChI:InChI=1/C7H6BrIO/c1-10-5-2-3-7(9)6(8)4-5/h2-4H,1H3

Upstream product

• 2398-37-0 3-methoxyphenyl bromide 
• 1037298-05-7 3-bromo-4-iodophenol 
• 74-88-4 methyl iodide 
• 1428963-74-9 3-bromo-4-iodophenyl methanesulfonate 
• 191719-02-5 4-amino-3-bromophenyl methanesulfonate 
• 24690-19-5 methanesulfonic acid 4-aminophenyl ester 
• 20455-07-6 p-nitrophenyl methanesulfonate 
• 100-02-7 4-nitro-phenol 

Downstream Products

• 1399743-45-3 C₁₉H₁₄BrNO 
• 1394248-15-7 tert-butyl 6-methoxyindoline-1-carboxylate 
• 1428963-59-0 tert-butyl 6-methoxy-7-(4-methoxyphenyl)indoline-1-carboxylate 
• 1428963-60-3 tert-butyl 6-methoxy-7-(4-(trifluoromethyl)phenyl)indoline-1-carboxylate 
• 1428963-61-4 tert-butyl 7-(4-bromophenyl)-6-methoxyindoline-1-carboxylate 
• 1428963-46-5 tert-butyl 7-deuterio-6-methoxyindoline-1-carboxylate 
• 1428963-66-9 tert-butyl 2-methoxy-1-(4-methoxyphenyl)-9H-carbazole-9-carboxylate 
• 113521-05-4 2-(2-bromo-4-methoxyphenyl)ethanamine 
• 1428963-75-0 N-benzyl-2-(2-bromo-4-methoxyphenyl)ethanamine 
• 1428963-76-1 C₂₄H₃₄BrNO₃S 
• 1428963-48-7 C₂₄H₃₂BrNO₃S 
• 1273546-88-5 tert-butyl 2-bromo-4-methoxyphenethylcarbamate 
• 1616624-58-8 (E)-[2-(2-bromo-4-methoxyphenyl)-1,2-diphenylvinyl]trimethylstannane 

Relevant articles and documents

Narrowing Segments of Helical Carbon Nanotubes with Curved Aromatic Panels

Rigid molecular cylinders with a 1 nm diameter were synthesized by assembling arylene panels with Pt-mediated macrocylization. Chrysenylene panels that previously participated in tetrameric macrocyclization were contorted by the addition of two benzo groups on the sides to form dibenzochrysenylene, which allowed for a reduction in the numbers of participating panels to three. Consequently, narrowed cyclochrysenylene congeners were obtained. The narrowed chiral cylinders possessed width-dependent chiroptical properties. The magnetic transition dipole moment was dictated by the radius of a ring-current-like circle that was formed by local electric transition dipole moments on the cylinder.

Methylene Bridging Effect on the Structures, Lewis Acidities and Optical Properties of Semi-planar Triarylboranes

Three synthetic methods towards semi-planar triarylboranes with two aryl rings connected by a methylene bridge have been developed. The fine-tuning of their stereoelectronic properties and Lewis acidities was achieved by introducing fluorine, methyl, methoxy, n-butyl and phenyl groups either at their exocyclic or bridged aryl rings. X-ray diffraction analysis and quantum-chemical calculations provided quantitative information on the structural distortion experienced by the near planar hydro-boraanthracene skeleton during the association with Lewis bases such as NH3 and F?. Though the methylene bridge between the ortho-positions of two aryl rings of triarylboranes decreased the Gibbs free energies of complexation with small Lewis bases by less than 5 kJ mol?1 relative to the classical Lewis acid BAr3, the steric shielding of the CH2 bridge is sufficient to avoid the formation of Lewis adducts with larger Lewis bases such as triarylphosphines. A newly synthesized spirocyclic amino-borane with a long intramolecular B?N bond that could be dissociated under thermal process, UV-irradiation, or acidic conditions might be a potential candidate in Lewis pairs catalysis.

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Gold(I)-catalyzed iodination of arenes

A wide variety of electron-rich arenes were efficiently converted into the corresponding iodinated compounds via a gold(I)-catalyzed reaction under mild conditions. Georg Thieme Verlag Stuttgart. New York.

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Cu(I)-mediated lactone formation in subcritical water: A benign synthesis of benzopyranones and urolithins A-C

Benzopyranones were successfully synthesized using Cu(I)-mediated C-O bond formation in subcritical water. A number of benzopyranone derivatives including polymethoxy benzopyranones, benzopyranopyridones, chromenoindolones, and furochromenones were synthesized in satisfactory yield. This methodology was further applied to synthesize the intestinal microbial metabolites, urolithins A, B, and C, which were found to exhibit potent antioxidant activity.

A total synthesis prompts the structure revision of haouamine B

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