4645-72-1

Basic information

• Product Name: N-hydroxy-N-phenyl-carbamic acid phenyl ester
• Synonyms: N-hydroxy-N-phenyl-carbamic acid phenyl ester
• CAS NO: 4645-72-1
• Molecular Weight: 229.235
• Mol File: 4645-72-1.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: N-hydroxy-N-phenyl-carbamic acid phenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: N-hydroxy-N-phenyl-carbamic acid phenyl ester(4645-72-1)
• EPA Substance Registry System: N-hydroxy-N-phenyl-carbamic acid phenyl ester(4645-72-1)

Safety Data

• Hazardous Substances Data: 4645-72-1(Hazardous Substances Data)

Upstream product

• 100-65-2 N-Phenylhydroxylamine 
• 1885-14-9 phenyl chloroformate 
• 22755-09-5 N-phenyl hydroxylamine hydrochloride 
• 98-95-3 nitrobenzene 

Downstream Products

• 495-48-7 Azoxybenzene 
• 62-53-3 aniline 
• 108-95-2 phenol 

Relevant articles and documents

Laccase Variants

The present invention relates to variants of a parent laccase. The present invention also relates to polynucleotides encoding the variant laccases and to nucleic acid constructs, vectors, and host cells comprising the polynucleotides, and methods of using the variant enzymes.

Kinetics and mechanism of base-catalysed degradations of substituted aryl-N-hydroxycarbamates, their N-methyl and N-phenyl analogues

The kinetics and mechanism of the degradation reactions of substituted phenyl N-hydroxycarbamates and their N-methyl and N-phenyl analogues have been studied at pseudo-first-order reaction conditions in aqueous buffers and sodium hydroxide solutions at 20°C and 60°C and at I = 1 mol·1 -1. The dependence of log kobs on pH for phenyl N-hydroxycarbamates at pH 13 is linear with the unit slope; at pH 10-12 log kobs is pH independent. The Bronsted coefficient βlg is about -1 (pH 7-13) and -1.53 (pH > 13) indicating that the degradation reaction of phenyl N-hydroxycarbamates follows an ElcB mechanism giving the corresponding phenol/phenolate and HO-N=C=O. The latter species undergoes further decomposition to give carbonate, nitrogen and ammonia as final products. In contrast to the phenyl N-hydroxycarbamates the N-methyl derivatives at pH 7-9 undergo degradation to the corresponding phenol/phenolate, carbonate and methylamine via a concerted mechanism (βlg is about - 0.75). The only exception is 4-nitrophenyl N-hydroxy-N-methylcarbamate in which the predominant break down pathway proceeds via the Smiles rearrangement to give sodium N-methyl-(4-nitrophenoxy)carbamate. At pH > 9 the reaction of N-hydroxy-N-methylcarbamates is kinetically complex: the dependence of absorbance on time is not exponential and it proceeds as a consecutive two-step reaction. N-Hydroxy-N-phenylcarbamate under the same conditions undergoes degradation to phenol, carbonate, aniline and azoxybenzene.

ANTIMICROBIAL COMPOSITION CONTAINING AN OXIDOREDUCTASE AND AN ENHANCER OF THER N-HYDROXYANILIDE-TYPE

The present invention relates to an enzymatic composition capable of killing or inhibiting microbial cells or micro-organisms, e.g. in laundry, on hard surfaces, in water systems, on skin, on teeth or on mucous membranes. The present invention also relate