4597-21-1 Usage
General Description
1H-Benzimidazole-5-carboxaldehyde,1,2-dimethyl-(9CI) is a chemical compound with a molecular formula of C10H10N2O. It is a derivative of benzimidazole, which is a heterocyclic compound that consists of a benzene ring fused to an imidazole ring. 1H-Benzimidazole-5-carboxaldehyde,1,2-dimethyl-(9CI) is commonly used in organic synthesis and pharmaceutical research due to its potential pharmacological activities, including anti-inflammatory, antibacterial, and antifungal properties. It is a yellow solid with a melting point of 198-200°C and has a wide range of applications in the chemical and pharmaceutical industries. Additionally, it is important for the development of new drugs and medicinal compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 4597-21-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,5,9 and 7 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 4597-21:
(6*4)+(5*5)+(4*9)+(3*7)+(2*2)+(1*1)=111
111 % 10 = 1
So 4597-21-1 is a valid CAS Registry Number.
4597-21-1Relevant articles and documents
Total synthesis of hypermodified epothilone analogs with potent in vitro antitumor activity
Kuzniewski, Christian N.,Gertsch, Jurg,Wartmann, Markus,Altmann, Karl-Heinz
supporting information; experimental part, p. 1183 - 1186 (2009/04/06)
The convergent total synthesis of hypermodified epothilone analogs 1 and 2 has been achieved with the stereoselective cyclopropanation of allylic alcohol 17 and ring-closing olefin metathesis with diene 22 as the key steps. In spite of significant structural differences between these analogs and the natural epothilone scaffold, 1 and 2 are potent inducers of tubulin polymerization and inhibit the growth of human cancer cells in vitro with sub-nM IC50 values.