4589-12-2 Usage
Description
N-(pyridin-2-yl)benzamide is a chemical compound characterized by the molecular formula C14H11N3O. It is an aromatic amide derivative featuring a benzene ring connected to a pyridine ring and a carbonyl group. N-(pyridin-2-yl)benzamide is recognized for its yellow solid form at room temperature, with limited solubility in water but good solubility in organic solvents. Its significance in the fields of medicinal chemistry and chemical synthesis is attributed to its potential as an intermediate in the production of pharmaceutical and agrochemical products, as well as its studied biological activities, such as enzyme and receptor inhibition.
Uses
Used in Pharmaceutical and Agrochemical Industries:
N-(pyridin-2-yl)benzamide serves as a crucial intermediate in the synthesis of various pharmaceutical and agrochemical products. Its unique structure allows for the development of compounds with specific therapeutic or pesticidal properties, contributing to the advancement of these industries.
Used in Medicinal Chemistry Research:
In the realm of medicinal chemistry, N-(pyridin-2-yl)benzamide is utilized for studying its potential biological activities. Its ability to inhibit certain enzymes and receptors makes it a valuable compound for exploring new therapeutic targets and developing novel drugs.
Used in Chemical Synthesis:
N-(pyridin-2-yl)benzamide's properties as a yellow solid with specific solubility characteristics make it an important compound in chemical synthesis. Its use in the creation of various chemical entities for different applications underscores its versatility and importance in the synthesis of complex organic molecules.
Check Digit Verification of cas no
The CAS Registry Mumber 4589-12-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,5,8 and 9 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 4589-12:
(6*4)+(5*5)+(4*8)+(3*9)+(2*1)+(1*2)=112
112 % 10 = 2
So 4589-12-2 is a valid CAS Registry Number.
4589-12-2Relevant articles and documents
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Huntress,Walter
, p. 735 (1948)
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Single-pot tandem oxidative/C-H modification amidation process using ultrasmall PdNP-encapsulated porous organosilica nanotubes
Gholipour, Behnam,Liu, Xiao,Rostamnia, Sadegh,Zonouzi, Afsaneh
, p. 4276 - 4287 (2022/02/16)
Herein, we studied a single-pot method with a dual catalysis process towards the conversion of primary aromatic alcohols to amides using ultrasmall PdNPs of controlled uniform size (1.8 nm) inside hybrid mesoporous organosilica nanotubes (MO-NTs). The cat
Metal-free oxidative decarbonylative halogenation of fused imidazoles
Kumar, Gulshan,Shankar, Ravi,Singh, Davinder,Tali, Javeed Ahmad
supporting information, p. 20551 - 20555 (2021/11/23)
An efficient strategy has been developed for the deformylative halogenation of carbaldehyde imidazo-fused heterocycles in the presence of TBHP controlled by temperature. A convenient and sequential functionalization (C8 to C3) portrays the synthetic utility of the current method.N-Heterocycle benzamide products were also observedviathe ring opening of imidazopyridines through the cleavage of C-C bond at high temperatures. Features of this method include temperature-controlled excellent regioselectivity, mild conditions and functional group tolerance.
Cu-catalyzed cross-coupling of methyl ketones and pyridin-2-amines for the synthesis of N-(2-pyridyl)-α-ketoamides
Chen, Ali,Yang, Daji,Yu, Yue,Liu, Xiang,Rao, Chuixiong,Lin, Haoming,Guo, Pengfeng
, p. 417 - 421 (2020/11/30)
An efficient copper-catalyzed strategy for the synthesis of α-ketoamides via cross-coupling of methyl ketones and pyridin-2-amines is described. This transformation has provided a simple process for the formation of C?N and C=O bonds to prepare α-ketoamid
