4544-20-1

Basic information

• Product Name: 2-Ethoxy-1,3-dioxolane
• Synonyms: 2-Ethoxy-1,3-dioxolane;2-ethoxy-1,3-dioxolane, ethyl ethylene orthoformate, 2-ethoxydioxolane, 2-ethoxy-[1,3]dioxolane, 2-Aethoxy-[1,3]dioxolan, 2-Ethoxy-1,3-dioxolan
• CAS NO: 4544-20-1
• Molecular Formula: C₅H₁₀O₃
• Molecular Weight: 118.13
• Mol File: 4544-20-1.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 137 ºC
• Flash Point: 41 ºC
• Appearance: /
• Density: 1.05
• Vapor Pressure: 9.04mmHg at 25°C
• Refractive Index: 1.419
• CAS DataBase Reference: 2-Ethoxy-1,3-dioxolane(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Ethoxy-1,3-dioxolane(4544-20-1)
• EPA Substance Registry System: 2-Ethoxy-1,3-dioxolane(4544-20-1)

Safety Data

• Hazardous Substances Data: 4544-20-1(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Production:
2-Ethoxy-1,3-dioxolane is used as a solvent or reagent in the synthesis of various pharmaceutical compounds due to its ability to dissolve a wide range of substances and facilitate chemical reactions.
Used in Polymer Production:
In the polymer industry, 2-Ethoxy-1,3-dioxolane serves as a solvent or reagent for the synthesis of specific polymers, contributing to the development of new materials with desired properties.
Used in Organic Compound Synthesis:
2-Ethoxy-1,3-dioxolane is utilized as a solvent or reagent in the synthesis of various organic compounds, enabling the production of a broad spectrum of chemical products.
Used in Electrolyte Solutions for Lithium-Ion Batteries:
2-Ethoxy-1,3-dioxolane is employed as a solvent in electrolyte solutions for lithium-ion batteries, enhancing their performance and stability.
Due to the potential health hazards associated with 2-Ethoxy-1,3-dioxolane, it is crucial to follow proper handling and safety precautions when using this chemical in any application.

InChI:InChI=1/C5H10O3/c1-2-6-5-7-3-4-8-5/h5H,2-4H2,1H3

Upstream product

• 110-63-4 Butane-1,4-diol 
• 122-51-0 orthoformic acid triethyl ester 
• 4544-19-8 1,2-di(1,3-dioxolan-2-yloxy)ethane 
• 107-21-1 ethylene glycol 
• 22432-65-1 2-butoxy-[1,3]dioxolane 
• 1825-62-3 ethyl trimethylsilyl ether 

Downstream Products

• 646-06-0 1,3-DIOXOLANE 
• 597-67-1 ethoxytriethylsilane 
• 13175-68-3 1,2-bis (triethylsilyloxy) ethane 
• 74733-99-6 2-<2-(2-methoxyethoxy)ethoxy>-1,3-dioxolan 
• 34909-25-6 diethyl <(ethylenedioxy)methyl>phosphonate 
• 78-40-0 triethyl phosphate 
• 96-49-1 [1,3]-dioxolan-2-one 
• 74-96-4 ethyl bromide 
• 6065-67-4 formic acid-(2-bromo-ethyl ester) 
• 36842-22-5 ethyl 2-bromoethyl carbonate 
• 75-07-0 acetaldehyde 
• 74-95-3 1,1-dibromomethane 
• 79-27-6 1,1,2,2-tetrabromoethane 
• 1825-62-3 ethyl trimethylsilyl ether 

Relevant articles and documents

TRANSFORMATIONS OF CYCLIC ORTHO MONO- AND DIESTERS BY THE ACTION OF FREE RADICALS IN THE LIQUID PHASE

The homolytic liquid-phase reactions of 2-propoxy-1,3-dioxane, 1,2-di(1,3-dioxolan-2-yloxy)ethane, and 1,3-di(1,3-dioxan-2-yloxy)propane, initiated by tert-butoxyl radicals, were investigated.A mechanism is proposed for the formation of dipropylcarbonate, 1,3-dioxan-2-one, propylformate, propionaldehyde, and propane from 2-propoxy-1,3-dioxane.The kinetic parameters characterizing the rate and direction of the transformations were determined.It was found that the corresponding linear and cyclic carbonates are mainly formed from the ortho diesters.

Preparation de cetals cycliques a plus de sept chainons

A good synthesis of eight-membered cyclic ketals, among them trioxocanes, is described.These products are obtained by direct reaction of a ketone on a substitute of orthoester.

EFFECT OF SUBSTITUENTS ON THE STABILITTY OF 1,3-DIOOXOLENIUM IONS

The 1,3-dioxolenium ions formed in the reaction of 2-isopropoxy-1,3-dioxolanes with fluorosulfonic acid were investigated by PMR spectroscopy.The stability of the cations depends linearly on the electron-donating ability of the substituents at positions 4 and 5 of the ring.The effect of the stability of the cations on the hydrolysis rate of 2-alkoxy-1,3-dioxolanes is discussed.

Reactions of Co-ordinated Ligands. Part 8. Reaction of Grignard Reagents with 2-Alkoxy-1,3-dioxolans; an Improved Route to Aldehydes

The yields of 2-phenyl-1,3-dioxolan obtained from phenylmagnesium bromide and 2-alkoxy-1,3-dioxolans in which the type Men-O increase as the value of n proceeds along the series 4,3,1,2.Several Grignard reagents(including phenylmagnesium bromide) react with the 2-alkoxy-1,3-dioxolan in which n=2 to give the expected 2-substituted-1,3-dioxolans, whose yields are considerably higher than those of the diethyl acetals obtained from the corresponding reation with ethyl ortoformate.