453518-19-9Relevant articles and documents
PROCESS FOR PREPARATION OF 2-AMINO-5-HYDROXY PROPIOPHENONE
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Page/Page column 33, (2020/07/31)
The present invention relates to a process for preparation of 2-Amino-5-hydroxypropiophenone, a key intermediate for the synthesis of camptothecin analogs including 7-Ethyl-10-hydroxycamptothecin (SN-38).
Method of Synthesizing Key Intermediates for the Production of Camptothecin Derivatives
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Page/Page column 5, (2008/12/08)
The present invention discloses a process for efficient production of 2-amino-5-hydroxypropiophenone corresponding to the AB ring part of camptothecin (CPT) skeleton, which is a key intermediate useful for the total synthesis of camptothecin analogs including 7-Ethyl-10-hydroxy camptothecin and novel intermediates thereof.
New benzo[5,6]pyrrolizino[1,2-b]quinolines as cytotoxic agents
Perzyna, Aurore,Klupsch, Frederique,Houssin, Raymond,Pommery, Nicole,Lemoine, Amelie,Henichart, Jean-Pierre
, p. 2363 - 2365 (2007/10/03)
An assessment of structure-activity relationships associated with the new benzo[5,6]pyrrolizino[1,2-b]quinoline system displaying potent in vitro cytotoxic activity against the MCF7 cell line is described.