4470-83-1 Usage
Description
2,8-Dichloroquinoline is an organic compound that can be synthesized from the reaction between 8-chloroquinoline-N-oxide and phosphoryl trichloride. It is a derivative of quinoline, a nitrogen-containing aromatic compound, with two chlorine atoms attached at the 2nd and 8th positions.
Uses
Used in Pharmaceutical Industry:
2,8-Dichloroquinoline is used as an intermediate in the synthesis of various pharmaceutical compounds for its potential therapeutic applications. It serves as a key building block in the development of new drugs.
Used in Chemical Synthesis:
2,8-Dichloroquinoline is used as a starting material for the neat synthesis of 8-chloro-2-(thiophen-2-ylsulfanyl)quinolone, which may have further applications in the pharmaceutical or chemical industries.
Additionally, it is used in the preparation of 2-methyl-4-[-2′-(8′-chloroquinolyl)]-but-3-yn-2-ol, which could be relevant in the development of new chemical compounds with specific properties and applications.
Check Digit Verification of cas no
The CAS Registry Mumber 4470-83-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,4,7 and 0 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 4470-83:
(6*4)+(5*4)+(4*7)+(3*0)+(2*8)+(1*3)=91
91 % 10 = 1
So 4470-83-1 is a valid CAS Registry Number.
InChI:InChI=1/C9H5Cl2N/c10-7-3-1-2-6-4-5-8(11)12-9(6)7/h1-5H
4470-83-1Relevant articles and documents
NITROGEN HETEROCYCLIC COMPOUNDS USEFUL AS PDE10 INHIBITORS
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Page/Page column 183, (2011/12/02)
Unsaturated nitrogen heterocyclic compounds of formula (I): (I), as defined in the specification, compositions containing them, and processes for preparing such compounds. Provided herein also are methods of treating disorders or diseases treatable by inhibition of PDE10, such as obesity, Huntington's Disease, non-insulin dependent diabetes, schizophrenia, bipolar disorder, obsessive-compulsive disorder, and the like.