42772-82-7 Usage
Description
O-HYDROXY-BETA-PHENYL PROPIOPHENONE, a pale yellow crystalline solid, is a chemical compound belonging to the class of beta-keto phenethylamines. It features a hydroxyl group and a phenyl group attached to a beta-ketone, making it a key building block for various synthetic reactions. Known for its role in the synthesis of advanced materials, O-HYDROXY-BETA-PHENYL PROPIOPHENONE is commonly used in the research and development of new chemical compounds, as well as an intermediate in the production of pharmaceuticals, dyes, and organic synthesis.
Uses
Used in Pharmaceutical Industry:
O-HYDROXY-BETA-PHENYL PROPIOPHENONE is used as an intermediate for the synthesis of various pharmaceuticals due to its unique chemical structure and reactivity, contributing to the development of new drugs and medications.
Used in Dye Industry:
O-HYDROXY-BETA-PHENYL PROPIOPHENONE is used as a key component in the production of dyes, leveraging its chemical properties to create a wide range of colorants for various applications.
Used in Organic Synthesis:
O-HYDROXY-BETA-PHENYL PROPIOPHENONE is used as a building block in organic synthesis, enabling the creation of complex organic compounds for research and commercial purposes.
Used in Research and Development:
O-HYDROXY-BETA-PHENYL PROPIOPHENONE is used as a research compound for the development of new chemical entities, exploring its potential applications and properties in various fields of chemistry and material science.
Check Digit Verification of cas no
The CAS Registry Mumber 42772-82-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,2,7,7 and 2 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 42772-82:
(7*4)+(6*2)+(5*7)+(4*7)+(3*2)+(2*8)+(1*2)=127
127 % 10 = 7
So 42772-82-7 is a valid CAS Registry Number.
InChI:InChI=1S/C15H14O2/c16-14-9-5-4-8-13(14)15(17)11-10-12-6-2-1-3-7-12/h1-9,16H,10-11H2
42772-82-7Relevant articles and documents
Rhodium-phosphoramidite catalyzed alkene hydroacylation: Mechanism and octaketide natural product synthesis
Von Delius, Max,Le, Christine M.,Dong, Vy M.
supporting information, p. 15022 - 15032 (2012/11/06)
We describe a method that allows salicylaldehyde derivatives to be coupled with a wide range of unactivated alkenes at catalyst loadings as low as 2 mol %. A chiral phosphoramidite ligand and the precise stoichiometry of heterogeneous base are key for high catalytic activity and linear regioselectivity. This protocol was applied in the atom- and step-economical synthesis of eight biologically active octaketide natural products, including anticancer drug candidate cytosporone B. Mechanistic studies provide insight on parameters affecting decarbonylation, a side reaction that limits the turnover number for catalytic hydroacylation. Deuterium labeling studies show that branched hydride insertion is fully reversible, whereas linear hydride insertion is largely irreversible and turnover-limiting. We propose that ligand (R a,R,R)-SIPHOS-PE effectively suppresses decarbonylation, and helps favor a turnover-limiting insertion, by lowering the barrier for reductive elimination in the linear-selective pathway. Together, these factors enable high reactivity and regioselectivity.
Synthesis of α-methyldeoxybenzoins
Salakka,Waehaelae
, p. 2601 - 2604 (2007/10/03)
Reduction of hydroxy and/or methoxy-substituted isoflavones using LiAlH4 in refluxing THF provides an easy access to a number of α-methyldeoxybenzoins, possible metabolites of phytoestrogens in man. The synthesis of O-demethylangolensin 2b, 6′-hydroxyangolensin 2c, angolensin 2d, 1-(2,4-dihydroxyphenyl)-2-phenylpropan-1-one 2e, 1-(2-hydroxy-4-methoxyphenyl)-2-(4-hydroxyphenyl)propan-1-one2f, 4′-O-methylangolensin 2g, 1-(2-hydroxy-4-methoxyphenyl)-2-phenylpropan-1-one 2h, and 1-(2-hydroxyphenyl)-2-phenylpropan-1-one 2i is described. The Royal Society of Chemistry 1999.
