42514-50-1

Basic information

• Product Name: 3-AMINO-3-METHYL-BUTAN-1-OL
• Synonyms: 3-AMINO-3-METHYL-BUTAN-1-OL;3-Amino-3-methyl-1-butanol;3-Amino-3-methyl-butan-I-ol;1-butanol, 3-amino-3-methyl-
• CAS NO: 42514-50-1
• Molecular Formula: C₅H₁₃NO
• Molecular Weight: 103.16282
• EINECS: 255-865-9
• Product Categories: pharmacetical
• Mol File: 42514-50-1.mol
• Article Data: 14

Chemical Properties

• Boiling Point: 179.2°Cat760mmHg
• Flash Point: 62.1°C
• Appearance: /
• Density: 0.918g/cm³
• Vapor Pressure: 0.285mmHg at 25°C
• Refractive Index: 1.451
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 15.42±0.10(Predicted)
• CAS DataBase Reference: 3-AMINO-3-METHYL-BUTAN-1-OL(CAS DataBase Reference)
• NIST Chemistry Reference: 3-AMINO-3-METHYL-BUTAN-1-OL(42514-50-1)
• EPA Substance Registry System: 3-AMINO-3-METHYL-BUTAN-1-OL(42514-50-1)

Safety Data

• RIDADR: 2735
• HazardClass: 8
• PackingGroup: Ⅲ
• Hazardous Substances Data: 42514-50-1(Hazardous Substances Data)

Usage

Description

3-Amino-3-methyl-butan-1-ol, also known by its IUPAC name as 3-Amino-3-methylbutan-1-ol, is a chemical compound with the formula C5H13NO. It is a member of the amino alcohol class, which includes organic compounds that contain both an alcohol and an amine group. 3-AMINO-3-METHYL-BUTAN-1-OL is primarily used as an intermediate in the production of other chemicals.

Uses

Used in Chemical Synthesis:
3-Amino-3-methyl-butan-1-ol is used as an intermediate in the production of various chemicals. Its unique structure allows it to be a valuable component in the synthesis of a wide range of compounds.
Used in Pharmaceutical Industry:
3-Amino-3-methyl-butan-1-ol is used as a building block in the development of pharmaceuticals. Its presence in amino alcohols makes it a potential candidate for the creation of new drug molecules.
Used in Research and Development:
3-Amino-3-methyl-butan-1-ol is utilized in research and development settings to explore its potential applications and properties. As a member of the amino alcohol class, it may contribute to the discovery of new chemical reactions and processes.

InChI:InChI=1/C5H13NO/c1-5(2,6)3-4-7/h7H,3-4,6H2,1-2H3

Upstream product

• 625-05-8 3-amino-3-methylbutanoic acid 
• 105090-72-0 3-azido-3-methylbutanoic acid 
• 541-47-9 3-Methylbutenoic acid 
• 6245-99-4 2,2-dimethyl-oxetane 
• 17945-55-0 3-Benzylamino-3-methyl-butan-1-ol 
• 766-15-4 4,4-dimethyl-1,3-dioxane 
• 75-86-5 2-hydroxy-2-methylpropanenitrile 
• 26939-09-3 2,4,4-trimethyl-5,6-dihydro-1,3(4H)-oxazine 
• 624-96-4 1,3-dichloro-3-methylbutane 
• 7664-41-7 ammonia 
• 81548-18-7 3-acetamido-3-methyl-1-butanol 
• 102222-61-7 (3-Isocyano-3-methyl-butoxy)-trimethyl-silane 
• 37139-42-7 4,4-dimethyl-2-vinyl-4H-5,6-dihydro-1,3-oxazine 

Downstream Products

• 187107-78-4 S-3-(benzyloxycarbonylamino)-3-methylbutyl ethanethioate 
• 1314079-85-0 C₂₁H₃₅NO₇S₂ 
• 1314079-84-9 C₁₉H₃₃N₂O₄S⁽¹⁺⁾*Cl^(1-) 
• 1226913-78-5 CHO₂^(1-)*C₁₉H₃₃N₂O₄S⁽¹⁺⁾ 
• 1226913-76-3 Br^(1-)*C₁₉H₃₃N₂O₂S⁽¹⁺⁾ 
• 1226913-83-2 CHO₂^(1-)*C₁₈H₃₁N₂O₄S⁽¹⁺⁾ 

Relevant articles and documents

Reaction of 4,4-dimethyl-1,3-dioxane with dinitriles

The reaction of 4,4-dimethyl-1,3-dioxane with bis(2-cyano)diethyl ether or 1,2-di(β-cyanoethoxy)-ethane yields the corresponding bis[2-(4,4-dimethyl-5,6-dihydro-2-oxazinyl)]diethyl ether and 1,2-di{β-[2-(4,4-dimethyl-5,6-dihydro-2-oxazinyl)]ethoxy} ethane

N,N-Dichloroaminosulfonic acids as novel topical antimicrobial agents

2-Dichloroamino-2-methyl-propane-1-sulfonic acid sodium salt (2a), a stable derivative of endogenous N,N-dichlorotaurine (1), has been identified and is under development as a topical antimicrobial agent. Structure-activity relationships of analogs were explored to achieve optimal antimicrobial activity with minimal mammalian toxicity while maintaining the desired stability. All the analogs synthesized showed antimicrobial activity against Staphylococcus aureus, Escherichia coli, and Candida albicans in the range of 1-128 μg/mL and cytotoxicity against mammalian L929 cells in the range 80-1900 μg/mL.

Aminoquinolones as GSK-3 inhibitors

Provided herein are aminoquinolones and pharmaceutically acceptable derivatives thereof. In certain embodiments, provided herein are compounds, compositions and methods for treating, preventing or ameliorating GSK-3 mediated diseases.