41780-53-4

Basic information

• Product Name: N'-(4-tert-butylcyclohexylidene)-4-Methylbenzenesulfonohydrazide
• Synonyms: N'-(4-tert-butylcyclohexylidene)-4-Methylbenzenesulfonohydrazide
• CAS NO: 41780-53-4
• Molecular Formula: C₁₇H₂₆N₂O₂S
• Molecular Weight: 322
• Mol File: 41780-53-4.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 444.7°Cat760mmHg
• Flash Point: 222.7°C
• Appearance: /
• Density: 1.14g/cm³
• CAS DataBase Reference: N'-(4-tert-butylcyclohexylidene)-4-Methylbenzenesulfonohydrazide(CAS DataBase Reference)
• NIST Chemistry Reference: N'-(4-tert-butylcyclohexylidene)-4-Methylbenzenesulfonohydrazide(41780-53-4)
• EPA Substance Registry System: N'-(4-tert-butylcyclohexylidene)-4-Methylbenzenesulfonohydrazide(41780-53-4)

Safety Data

• Hazardous Substances Data: 41780-53-4(Hazardous Substances Data)

Usage

Description

N'-(4-tert-butylcyclohexylidene)-4-Methylbenzenesulfonohydrazide is a chemical compound with the molecular formula C18H26N2O2S. It is a sulfonohydrazide derivative known for its hydrazine-like reactivity and ability to form covalent bonds with other molecules. Its unique structure, featuring tert-butylcyclohexylidene and methylbenzenesulfonohydrazide groups, endows it with distinctive chemical properties, making it valuable in various scientific applications. It also holds potential in the development of new drugs and materials due to its capacity to modify and functionalize other molecules.

Uses

Used in Organic Synthesis:
N'-(4-tert-butylcyclohexylidene)-4-Methylbenzenesulfonohydrazide is used as a reagent in organic synthesis for its ability to participate in various chemical reactions, facilitating the formation of new compounds and structures.
Used in Pharmaceutical Research:
In pharmaceutical research, N'-(4-tert-butylcyclohexylidene)-4-Methylbenzenesulfonohydrazide is utilized as a reagent to explore its potential in drug development. Its unique chemical properties and reactivity make it a candidate for creating novel pharmaceutical agents.
Used in Material Development:
N'-(4-tert-butylcyclohexylidene)-4-Methylbenzenesulfonohydrazide is also used in the development of new materials, where its capacity to modify and functionalize other molecules can lead to the creation of advanced materials with specific properties for various applications.

Upstream product

• 98-53-3 4-tercbutyl-cyclohexanone 
• 1576-35-8 toluene-4-sulfonic acid hydrazide 
• 81842-54-8 4-t-Butyl-2-nitrocyclohexanone 
• 85814-70-6 C₁₇H₂₅N₃O₄S 

Downstream Products

• 1512864-28-6 2,2'-(4-(tert-butyl)cyclohexane-1,1-diyl)bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolane) 
• 1429338-00-0 benzoyl(2-(4-tert-butylcyclohexyl)pyridinium-1-yl)azanide 
• 175284-37-4 4-tert-butylcyclohexyl pivalate 
• 83587-48-8 (2-(4-(tert-butyl)cyclohexylidene)ethyl)benzene 
• 1379610-66-8 2-(4-(tert-butyl)cyclohexyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 1379610-64-6 2-(4-(tert-butyl)cyclohexyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 287944-06-3 2-(4-(tert-butyl)cyclohex-1-en-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 319457-67-5 4-tert-Butyl-1-[(methoxymethoxy)methyl]cyclohex-1-ene 
• 54923-65-8 (4-tert-Butylcyclohex-1-enyl)methanol 
• 98-53-3 4-tercbutyl-cyclohexanone 
• 76421-27-7 4-tert-butyl-6-n-butylcyclohexene-1-carboxaldehyde 
• 23525-05-5 1-bromo-4-(tert-butyl)cyclohex-1-ene 
• 19422-34-5 1,1-difluoro-4-t-butylcyclohexane 
• 3178-22-1 tert-butylcyclohexane 

Relevant articles and documents

Umpolung Difunctionalization of Carbonyls via Visible-Light Photoredox Catalytic Radical-Carbanion Relay

The combination of photoredox catalysis with the Wolff-Kishner (WK) reaction allows the difunctionalization of carbonyl groups by a radical-carbanion relay sequence (photo-Wolff-Kishner reaction). Photoredox initiated radical addition to N-sulfonylhydrazones yields α-functionalized carbanions following the WK-type mechanism. With sulfur-centered radicals, the carbanions are further functionalized by reaction with electrophiles including CO2 and aldehydes, whereas CF3 radical addition furnishes a wide range of gem-difluoroalkenes through β-fluoride elimination of the generated α-CF3 carbanions. More than 80 substrate examples demonstrate the broad applicability of this reaction sequence. A series of investigations including radical inhibition, deuterium labeling, fluorescence quenching, cyclic voltammetry, and control experiments support the proposed radical-carbanion relay mechanism.

Catalyst-free synthesis of spiropyrazolines from chalcones and cyclic ketone N -tosylhydrazones

Treatment of cyclic ketone N-tosylhydrazones with chalcones in the presence of cesium carbonate at 110 °C affords spiropyrazolines with high selectivity and excellent yields. This protocol possesses many advantages such as readily available and stable sta

Formal carbon insertion of n-tosylhydrazone into B-B and B-Si bonds: Gem-diborylation and gem-silylborylation of sp3 carbon

A convenient method is developed to synthesize 1,1-diboronates from the corresponding N-tosylhydrazones. This method is also applicable to synthesize 1-silyl-1-boron compounds. Meanwhile, derivatization and consecutive Pd-catalyzed cross-coupling reaction