41204-59-5

Basic information

• Product Name: 4-METHOXY-2'-METHYLBENZOPHENONE
• Synonyms: 4-METHOXY-2'-METHYLBENZOPHENONE;UKRORGSYN-BB BBV-5119100
• CAS NO: 41204-59-5
• Molecular Formula: C₁₅H₁₄O₂
• Molecular Weight: 226.27
• Mol File: 41204-59-5.mol
• Article Data: 39

Chemical Properties

• Boiling Point: 336.9°C at 760 mmHg
• Flash Point: 144.3°C
• Appearance: /
• Density: 1.088g/cm³
• Vapor Pressure: 0.000108mmHg at 25°C
• Refractive Index: 1.563
• CAS DataBase Reference: 4-METHOXY-2'-METHYLBENZOPHENONE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-METHOXY-2'-METHYLBENZOPHENONE(41204-59-5)
• EPA Substance Registry System: 4-METHOXY-2'-METHYLBENZOPHENONE(41204-59-5)

Safety Data

• Hazardous Substances Data: 41204-59-5(Hazardous Substances Data)

Usage

InChI:InChI=1/C15H14O2/c1-11-5-3-4-6-14(11)15(16)12-7-9-13(17-2)10-8-12/h3-10H,1-2H3

Upstream product

• 201230-82-2 carbon monoxide 
• 16419-60-6 2-Methylphenylboronic acid 
• 459-64-3 4-methoxybenzenediazonium tetrafluoroborate 
• 33872-80-9 o-tolyl magnesium chloride 
• 100-07-2 4-methoxy-benzoyl chloride 
• 93296-09-4 4-methoxyphenylzinc chloride 
• 933-88-0 ortho-toluoyl chloride 
• 13139-86-1 4-methoxyphenyl magnesium bromide 
• 529-20-4 2-methylphenyl aldehyde 
• 1227475-35-5 (methyl)bis(2-tolyl)silane 
• 696-62-8 para-iodoanisole 
• 104-92-7 1-bromo-4-methoxy-benzene 
• 5720-07-0 4-methoxyphenylboronic acid 
• 213596-33-9 2-(4-methoxyphenyl)-5,5-dimethyl-1,3,2-dioxaborolane 

Downstream Products

• 52981-01-8 4-hydroxyphenyl 2-methylphenyl ketone 
• 50439-04-8 [2-(4-methoxy-benzoyl)-phenyl]-acetic acid 
• 220583-41-5 4-methoxyphenyl(2-methylphenyl)methanol 
• 1312211-05-4 C₁₈H₂₀O₂ 
• 1312210-86-8 C₁₈H₁₈O₂ 
• 66938-62-3 (4-Amino-3-nitro-phenyl)-o-tolyl-methanone 

Relevant articles and documents

Photo-induced oxidative cleavage of C-C double bonds for the synthesis of biaryl methanoneviaCeCl3catalysis

A Ce-catalyzed strategy is developed to produce biaryl methanonesviaphotooxidative cleavage of C-C double bonds at room temperature. This reaction is performed under air and demonstrates high activity as well as functional group tolerance. A synergistic Ce/ROH catalytic mechanism is also proposed based on the experimental observations. This protocol should be the first successful Ce-catalyzed photooxidation reaction of olefins with air as the oxidant, which would provide inspiration for the development of novel Ce-catalyzed photochemical synthesis processes.

Chiral electron-rich PNP ligand with a phospholane motif: Structural features and application in asymmetric hydrogenation

Despite the remarkable reactivity that was achieved by a series of transition-metal catalysts with a PNP type ligand, the electron-rich chiral PNP ligands have still been rarely reported because of the difficulties in synthesis and the nature of air-sensitivity. Herein, we report a novel chiral PNP ligand (Heng-PNP) with both a rigid backbone and a bulky tert-butyl group on the phospholane motif. We successfully obtained its divalent iron complex. The chiral environment of its Ir(III) complex was also discussed with quadrant analysis. This tridentate ligand was applied in iridium-catalyzed asymmetric hydrogenation of challenging diaryl ketones: up to 98% ee and 500 TON are achieved. Computational study showed that the twist of conjugate aryl group in the substrate (induced by the special chiral pocket of Ir/Heng-PNP complex) leads to the energy difference in the enantiodetermining step.

Arylation of Aldehydes to Directly Form Ketones via Tandem Nickel Catalysis

A nickel-catalyzed arylation of both aliphatic and aromatic aldehydes proceeds with air-stable (hetero)arylboronic acids, with an exceptionally wide substrate scope. The neutral condition tolerates acidic hydrogen and sensitive polar groups and also preserves α-stereocenters of some chiral aldehydes. Interestingly, this nickel(0) catalysis does not follow common 1,2-insertion of arylmetal species to aldehydes and β-hydrogen elimination.