41137-10-4

Basic information

• Product Name: N-Acetyl-D-glucosaminyl-(1-4)-N-acetylmuramic Acid
• Synonyms: N-Acetyl-4-O-[2-(acetylamino)-2-deoxy-b-D-glucopyranosyl]-muramic Acid;N-Acetyl-D-glucosaminyl-(1-4)-N-acetylmuramic Acid;2-Acetamido-4-O-(2-acetamido-2-deoxy-b-D-glucopyranosyl)-2-deoxy-D-muramicacid;N-Acetyl-4-O-[2-(acetylamino)-2-deoxy--D-glucopyranosyl]-muramic Acid
• CAS NO: 41137-10-4
• Molecular Formula: C19H32N2O13
• Molecular Weight: 496.463
• Product Categories: Oligosaccharides
• Mol File: 41137-10-4.mol
• Article Data: 0

Chemical Properties

• Melting Point: 169-171°C
• Boiling Point: 948.882 °C at 760 mmHg
• Flash Point: 527.665 °C
• Appearance: /
• Density: 1.531 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.591
• Storage Temp.: -20?C Freezer, Under Inert Atmosphere
• Solubility: Methanol (Slightly, Sonicated), Water (Slightly, Heated)
• CAS DataBase Reference: N-Acetyl-D-glucosaminyl-(1-4)-N-acetylmuramic Acid(CAS DataBase Reference)
• NIST Chemistry Reference: N-Acetyl-D-glucosaminyl-(1-4)-N-acetylmuramic Acid(41137-10-4)
• EPA Substance Registry System: N-Acetyl-D-glucosaminyl-(1-4)-N-acetylmuramic Acid(41137-10-4)

Safety Data

• Hazardous Substances Data: 41137-10-4(Hazardous Substances Data)

Usage

Description

N-Acetyl-D-glucosaminyl-(1-4)-N-acetylmuramic Acid is a complex carbohydrate molecule that plays a crucial role in the structure and function of bacterial cell walls. It is a disaccharide composed of N-acetyl-D-glucosamine and N-acetylmuramic acid, linked together by a β(1-4) glycosidic bond. N-Acetyl-D-glucosaminyl-(1-4)-N-acetylmuramic Acid is an essential component of peptidoglycan, which provides mechanical strength and shape to bacterial cells.

Uses

Used in Pharmaceutical Industry:
N-Acetyl-D-glucosaminyl-(1-4)-N-acetylmuramic Acid is used as a target for antibiotic development due to its presence in bacterial cell walls. It is a potential therapeutic agent for treating bacterial infections, as it can be exploited by antibiotics to disrupt the synthesis or integrity of peptidoglycan, leading to bacterial cell death.
Used in Research and Development:
N-Acetyl-D-glucosaminyl-(1-4)-N-acetylmuramic Acid is used as a research tool for studying the structure, function, and biosynthesis of bacterial cell walls. It can also be employed in the development of new antimicrobial agents and understanding the mechanisms of bacterial resistance to existing antibiotics.
Used in Immunology:
N-Acetyl-D-glucosaminyl-(1-4)-N-acetylmuramic Acid is used as an activator of human monocytes, which are immune cells that can destroy tumor cells. This property makes it a potential candidate for cancer immunotherapy, where the immune system is harnessed to fight cancer.
Used in Material Science:
As a component of peptidoglycan, N-Acetyl-D-glucosaminyl-(1-4)-N-acetylmuramic Acid may have potential applications in the development of novel biomaterials with unique mechanical properties, inspired by the structural characteristics of bacterial cell walls.
Used in Chemical Synthesis:
N-Acetyl-D-glucosaminyl-(1-4)-N-acetylmuramic Acid can be used as a building block or intermediate in the synthesis of various complex carbohydrates, glycoconjugates, and other biomolecules with potential applications in pharmaceuticals, diagnostics, and biotechnology.

InChI:InChI=1/C19H32N2O13/c1-6(17(28)29)31-16-12(21-8(3)25)18(30)32-10(5-23)15(16)34-19-11(20-7(2)24)14(27)13(26)9(4-22)33-19/h6,9-16,18-19,22-23,26-27,30H,4-5H2,1-3H3,(H,20,24)(H,21,25)(H,28,29)/t6-,9?,10?,11?,12-,13+,14?,15+,16+,18+,19-/m0/s1