41037-15-4

Basic information

• Product Name: 1-Methoxy-5-methylnaphthalene
• Synonyms: 1-Methoxy-5-methylnaphthalene
• CAS NO: 41037-15-4
• Molecular Formula: C12H12O
• Molecular Weight: 172.22308
• Mol File: 41037-15-4.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-Methoxy-5-methylnaphthalene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Methoxy-5-methylnaphthalene(41037-15-4)
• EPA Substance Registry System: 1-Methoxy-5-methylnaphthalene(41037-15-4)

Safety Data

• Hazardous Substances Data: 41037-15-4(Hazardous Substances Data)

Usage

Physical state

Colorless liquid

Odor

Faint, sweet

Solubility

Insoluble in water, soluble in organic solvents

Primary use

Fragrance and flavoring agent

Applications

Cosmetics, personal care products, household cleaners, dyes, pharmaceuticals, and other industrial applications

Toxicity

Low toxicity

Potential health effects

Skin, eye, and respiratory system irritation

Safety measures

Proper handling and precautions required during use

Upstream product

• 33892-75-0 5-Methoxy-1-tetralone 
• 90295-47-9 1,2-dihydro-4-methyl-8-methoxynaphthalene 
• 865070-96-8 5-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-1-ol 

Downstream Products

• 290365-70-7 1-(2-bromo-5-methyl-naphthalen-1-yloxy)-propan-2-one 
• 802910-33-4 4-hydroxy-7-methyl-benzo[h]chromen-2-one 

Relevant articles and documents

Antitumor agents. 239. Isolation, structure elucidation, total synthesis, and anti-breast cancer activity of neo-tanshinlactone from Salvia miltiorrhiza

Neo-tanshinlactone (1) was isolated and synthesized for the first time and evaluated in vitro against several human cancer cell lines. Compound 1 showed significant inhibition against two ER+ human breast cancer cell lines and was 10-fold more potent and 20-fold more selective as compared to tamoxifen citrate. Compound 1 also potently inhibited an ER-, HER-2 overexpressing breast cancer cell line. Therefore, this novel compound merits further development as an anti-breast cancer drug candidate.

Synthesis of some substituted naphthalenes as potential intermediates for polyethers and terpenoids

1-Benzyloxy-5-hydroxynaphthalene and 1,6-dimethyl-5-hydroxynaphthalene were prepared from 5-methoxy-α-tetralone. 6-Methoxy-α-tetralone was converted to 1,6-dimethoxy-2-isopropylnaphthalene.