406-86-0 Usage
Description
4,4,4-Trifluorocrotonitrile, also known as 4,4,4-TRIFLUOROCROTONITRILE, is an organic compound that features a trifluoromethyl group and a nitrile functional group. It is a valuable synthetic intermediate in the chemical industry due to its unique reactivity and properties.
Uses
Used in Pharmaceutical Industry:
4,4,4-Trifluorocrotonitrile is used as a synthetic intermediate for the production of trifluoromethylated pyridine derivatives, which are important building blocks in the development of various pharmaceutical compounds. These derivatives exhibit a range of biological activities, including anti-inflammatory, anti-cancer, and anti-microbial properties.
Used in Chemical Industry:
In the chemical industry, 4,4,4-Trifluorocrotonitrile is utilized as a key intermediate in the synthesis of substituted thiophenes. These substituted thiophenes are essential components in the manufacturing of various chemicals, materials, and dyes, as well as in the development of novel electronic and optoelectronic devices.
Used in Synthesis of Fluorinated Compounds:
4,4,4-Trifluorocrotonitrile is also used in the synthesis of other fluorinated compounds, such as 4,4,4-Trifluoro-2-butenenitrile. These fluorinated compounds have a wide range of applications, including agrochemicals, pharmaceuticals, and materials science, due to their unique properties and reactivity.
Check Digit Verification of cas no
The CAS Registry Mumber 406-86-0 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,0 and 6 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 406-86:
(5*4)+(4*0)+(3*6)+(2*8)+(1*6)=60
60 % 10 = 0
So 406-86-0 is a valid CAS Registry Number.
InChI:InChI=1/C4H2F3N/c5-4(6,7)2-1-3-8/h1-2H/b2-1+
406-86-0Relevant articles and documents
A 4, 4, 4-trifluoro-2-crotonization preparation method
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Paragraph 0031; 0032, (2017/03/21)
The invention discloses a preparation method for 4,4,4-trifluoro-2-crotononitrile. 4,4,4-trifluoro-2-crotononitrile is produced by reacting 3,3,3-trifluoro-1-chloropropene with sodium cyanide or potassium cyanide in a polar proton inert solvent under the effect of a phase transfer catalyst and a polymerization inhibitor. The preparation method provided by the invention is novel in synthesis route, easily available in raw materials and low in cost, and can significantly reduce production cost of 4,4,4-trifluoro-2-crotononitrile. The prepared 4,4,4-trifluoro-2-crotononitrile can be used for synthesizing fluorine-containing heterocyclic pesticides and medicines.
