40054-40-8 Usage
Description
5-(O-CHLOROPHENYL)-7-ETHYL-1,2-DIHYDRO-3H-THIENO[2,3-E][1,4]DIAZEPINE-2-THIONE is a thienodiazepine derivative with an O-chlorophenyl group and an ethyl group attached to the 7th position of the diazepine ring, and a thione group attached to the 2nd position. It belongs to the thienodiazepine class of drugs and exhibits various pharmacological properties, such as sedative, anxiolytic, and muscle relaxant effects. 5-(O-CHLOROPHENYL)-7-ETHYL-1,2-DIHYDRO-3H-THIENO[2,3-E][1,4]DIAZEPINE-2-THIONE has been studied for its potential use in treating anxiety, insomnia, and other central nervous system disorders, and may also possess anticonvulsant and hypnotic properties. Further research is required to fully understand its therapeutic applications and safety profile.
Uses
Used in Pharmaceutical Industry:
5-(O-CHLOROPHENYL)-7-ETHYL-1,2-DIHYDRO-3H-THIENO[2,3-E][1,4]DIAZEPINE-2-THIONE is used as a sedative, anxiolytic, and muscle relaxant for the treatment of anxiety, insomnia, and other central nervous system disorders. Its pharmacological properties make it a promising candidate for the development of new therapeutic agents to address these conditions.
Used in Research and Development:
5-(O-CHLOROPHENYL)-7-ETHYL-1,2-DIHYDRO-3H-THIENO[2,3-E][1,4]DIAZEPINE-2-THIONE is used in research and development for exploring its potential therapeutic applications, including anticonvulsant and hypnotic properties. Further studies are needed to understand its safety profile and optimize its use in various medical conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 40054-40-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,0,0,5 and 4 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 40054-40:
(7*4)+(6*0)+(5*0)+(4*5)+(3*4)+(2*4)+(1*0)=68
68 % 10 = 8
So 40054-40-8 is a valid CAS Registry Number.
40054-40-8Relevant articles and documents
Therapeutic agent for osteoporosis and diazepine compound
-
, (2008/06/13)
A therapeutic agent for osteoporosis, comprising an azepine compound of the formula STR1 wherein each symbol is as defined in the specification, or a pharmaceutically acceptable salt thereof as an active ingredient, a method for treating osteoporosis comprising administering said compound and a use of said compound for the production of a therapeutic agent for osteoporosis. The compounds of the formula (I) have superior bone resorption-inhibitory activity and act to reduce the increased amount of calcium in blood serum, which is caused by bone resorption. Accordingly, these compounds are usable as pharmaceutical agents to effectively inhibit bone resorption, to prevent decrease of bone mass and to prevent or suppress the increase of calcium amount in blood serum which is caused by the progress of bone resorption, with regard to Paget's disease, hypercalcemia, osteoporosis and so on in which the progress of bone resorption is considered to be deeply associated with the symptom, and to the symptoms of progressing bone resorption (development into osteoporosis) along with inflammatory joint diseases such as rheumatoid arthritis.
Syntheses and structure-activity relationships of 6-Aryl-4H-s-triazolo[3,4-c]thieno[2,3-e][1,4]diazepines
Tahara,Araki,Shiroki,Matsuo,Munakata
, p. 1153 - 1158 (2007/10/08)
A variety of 6 aryl 4H s triazolo [3,4-c]thieno [2,3-e] [1,4]diazepines was synthesized and tested for anti-pentylenetetrazole activity and inhibition of fighting episodes. The structure-activity relationships are discussed. Some compounds were more active than diazepam in the two assays. Among them, 6 (o chlorophenyl) 8 ethyl 1 methyl 4H s triazolo [3,4-c] thieno [2,3-e][1,4] diazepine was found to have favourable properties as an anxiolytic drug with very low toxicity. Clinical studies of this compound (Y-7131) are under way.