40027-96-1

Basic information

• Product Name: phenylthiomethyl 2-thienyl ketone
• Synonyms: phenylthiomethyl 2-thienyl ketone
• CAS NO: 40027-96-1
• Molecular Weight: 234.343
• Mol File: 40027-96-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: phenylthiomethyl 2-thienyl ketone(CAS DataBase Reference)
• NIST Chemistry Reference: phenylthiomethyl 2-thienyl ketone(40027-96-1)
• EPA Substance Registry System: phenylthiomethyl 2-thienyl ketone(40027-96-1)

Safety Data

• Hazardous Substances Data: 40027-96-1(Hazardous Substances Data)

Upstream product

• 10531-41-6 2-Bromoacetylthiophene 
• 930-69-8 sodium thiophenolate 
• 188290-36-0 thiophene 
• 7031-27-8 (phenylthio)acetic acid chloride 
• 103-04-8 (phenylthio)acetic acid 
• 108-98-5 thiophenol 

Relevant articles and documents

Catalytic Asymmetric [4 + 1] Annulation of Sulfur Ylides with Copper-Allenylidene Intermediates

The first copper-catalyzed asymmetric decarboxylative [4 + 1] cycloaddition of propargylic carbamates and sulfur ylides was successfully developed. This strategy led to a series of chiral indolines with synthetically flexible alkyne groups in good yields and with high enantio- and diastereoselectivities (up to 99% yield, 98% ee, and >95:5 dr). A possible mechanism and stereoinduction mode with copper-allenylidenes were proposed as the possible dipolar intermediate.

A CONVENIENT GENERAL ACCESS TO α-SULFENYLATED ACETOPHENONES AND ALKANONES

Friedel-Crafts acylation of arenes with methylthio- (1) or phenylthio-acetyl chloride (2) provides ready access to α-methylthio- or α-phenylthio-substituted acetophenones.The acyl chlorides 1 and 2 reacted also with organoaluminium reagents to give α-sulfenylated alkanones.