39638-34-1 Usage
Description
(R)-2-hydroxy-4-(methylthio)butyric acid is a chiral compound derived from a butyric acid molecule, featuring a hydroxy group and a methylthio group at specific positions. The (R)prefix denotes the orientation of its chiral center, and it is naturally occurring, playing a crucial role as a precursor in the biosynthesis of methionine, an essential amino acid, and in the production of the sulfur-containing antioxidant glutathione.
Uses
Used in Pharmaceutical and Nutritional Applications:
(R)-2-hydroxy-4-(methylthio)butyric acid is utilized as an intermediate in the synthesis of methionine, which is vital for protein synthesis and various metabolic processes in the body. It contributes to the maintenance of good health and supports the body's methylation cycle.
Used in Antioxidant Production:
(R)-2-hydroxy-4-(methylthio)butyric acid serves as a precursor for the production of glutathione, a tripeptide that acts as a powerful antioxidant and detoxifier in the body, protecting cells from oxidative stress and supporting the immune system.
Used in the Fermentation Industry:
(R)-2-hydroxy-4-(methylthio)butyric acid is employed as a feed additive in the livestock industry, where it enhances animal performance and health by supporting their metabolic processes and contributing to the efficient synthesis of essential amino acids and antioxidants.
Used in Agricultural Applications:
In agriculture, this compound can be used to improve the nutritional content of crops, potentially increasing their methionine and glutathione levels, which can have positive effects on crop health and yield.
Check Digit Verification of cas no
The CAS Registry Mumber 39638-34-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,9,6,3 and 8 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 39638-34:
(7*3)+(6*9)+(5*6)+(4*3)+(3*8)+(2*3)+(1*4)=151
151 % 10 = 1
So 39638-34-1 is a valid CAS Registry Number.
InChI:InChI=1/C5H10O3S/c1-9-3-2-4(6)5(7)8/h4,6H,2-3H2,1H3,(H,7,8)/t4-/m1/s1
39638-34-1Relevant articles and documents
Light-Driven Kinetic Resolution of α-Functionalized Carboxylic Acids Enabled by an Engineered Fatty Acid Photodecarboxylase
Xu, Jian,Hu, Yujing,Fan, Jiajie,Arkin, Mamatjan,Li, Danyang,Peng, Yongzhen,Xu, Weihua,Lin, Xianfu,Wu, Qi
supporting information, p. 8474 - 8478 (2019/05/24)
Chiral α-functionalized carboxylic acids are valuable precursors for a variety of medicines and natural products. Herein, we described an engineered fatty acid photodecarboxylase (CvFAP)-catalyzed kinetic resolution of α-amino acids and α-hydroxy acids, which provides the unreacted R-configured substrates with high yields and excellent stereoselectivity (ee up to 99 %). This efficient light-driven process requires neither NADPH recycling nor prior preparation of esters, which were required in previous biocatalytic approaches. The structure-guided engineering strategy is based on the scanning of large amino acids at hotspots to narrow the substrate binding tunnel. To the best of our knowledge, this is the first example of asymmetric catalysis by an engineered CvFAP.
A Convenient Route to (R)-α-Hydroxy Carboxylic Acids and (2R)-1-Amino-2-alkanols from (R)-Cyanohydrins
Ziegler, Thomas,Hoersch, Brigitte,Effenberger, Franz
, p. 575 - 578 (2007/10/02)
(R)-Cyanohydrins, prepared in good to excellent yields with high optical purity by enzyme-catalyzed addition of hydrogen cyanide to aldehydes in organic solvents, are hydrolyzed with concentrated hydrochloric acid at ambient temperature, usually in very high yield, without any trace of racemization to give (R)-α-hydroxy carboxylic acids.Likewise, no racemization is observed by direct reduction of the (R)-cyanohydrins with lithium aluminium hydride to give (2R)-1-amino-2-alkanols.
