3959-13-5

Basic information

• Product Name: methylphenylsilanediol
• Synonyms: methylphenylsilanediol;Methyldihydroxyphenylsilane;Methylphenyldihydroxysilane;Phenyl(methyl)dihydroxysilane;Einecs 223-562-0;Silanediol, methylphenyl-
• CAS NO: 3959-13-5
• Molecular Formula: C₇H₁₀O₂Si
• Molecular Weight: 154.2386
• EINECS: 223-562-0
• Mol File: 3959-13-5.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 250.6 °C at 760 mmHg
• Flash Point: 105.4 °C
• Appearance: /
• Density: 1.12 g/cm³
• Vapor Pressure: 0.0112mmHg at 25°C
• Refractive Index: 1.542
• Storage Temp.: Hygroscopic, Refrigerator, under inert atmosphere
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• CAS DataBase Reference: methylphenylsilanediol(CAS DataBase Reference)
• NIST Chemistry Reference: methylphenylsilanediol(3959-13-5)
• EPA Substance Registry System: methylphenylsilanediol(3959-13-5)

Safety Data

• Hazardous Substances Data: 3959-13-5(Hazardous Substances Data)

Usage

Description

Methylphenylsilanediol is an organic compound that features a silicon atom bonded to a phenyl group and two hydroxyl groups. It is known for its unique chemical properties and potential applications in various fields.

Uses

Used in Pharmaceutical Industry:
Methylphenylsilanediol is used as a reagent for the synthetic preparation of (tetramethylnapthalenyl)silanol derivatives. These derivatives are of interest due to their potential activity as selective inhibitors of adult T-cell leukemia (ATL). methylphenylsilanediol plays a crucial role in the development of novel therapeutic agents targeting specific types of cancer.
Used in Chemical Research:
In the field of chemical research, methylphenylsilanediol serves as a valuable compound for studying the properties and reactions of organosilicon compounds. Its unique structure allows for exploration into various chemical reactions and potential applications in material science and organic synthesis.

InChI:InChI=1/C7H10O2Si/c1-10(8,9)7-5-3-2-4-6-7/h2-6,8-9H,1H3

Upstream product

• 775-56-4 diethoxy-methyl-phenyl-silane 
• 149-74-6 dichloromethylphenylsilane 
• 3027-21-2 dimethoxy(methyl)phenylsilane 
• 766-08-5 methylphenylsilane 
• 31650-28-9 bis(2-thienyl)methylphenylsilane 
• 75-54-7 Dichloromethylsilane 

Downstream Products

• 56764-49-9 C₉H₁₄Cl₄O₂Si₃ 
• 56764-59-1 C₂₉H₃₆Cl₆O₆Si₇ 
• 56764-51-3 C₇H₈Cl₆O₂Si₃ 
• 56764-50-2 C₁₉H₁₈Cl₄O₂Si₃ 
• 1415933-87-7 1,5-divinyl-1,1,5,5-tetramethoxy-3-phenyl-3-methyltrisiloxane 
• 64793-12-0 2,2,6,6-Tetraethoxy-4,8-dimethyl-4,8-diphenyl-[1,3,5,7,2,4,6,8]tetroxatetrasilocane 
• 106582-62-1 1-hydro-1,3,3,5,7,7-hexamethyl-5-phenylcyclotetrasiloxane 
• 499777-17-2 1,1,3,5,5-pentamethyl-3-phenyltrisiloxane-1,5-diol 
• 92-52-4 biphenyl 
• 613-37-6 4-methoxylbiphenyl 
• 53040-92-9 4-(4-tolyl)anisole 
• 17962-87-7 1,5-dichloro-1,1,3,5,5-pentamethyl-3-phenyltrisiloxane 
• 64793-13-1 2,2,6,6-Tetraethoxy-4,4,8-trimethyl-8-phenyl-[1,3,5,7,2,4,6,8]tetroxatetrasilocane 
• 56792-10-0 C₁₁H₁₄Cl₄O₂Si₃ 

Relevant articles and documents

METHOD FOR PRODUCING SILANOLS AND NOVEL SILANOLS

PROBLEM TO BE SOLVED: To provide a method for efficiently producing silanols useful as functional chemicals, and to provide novel silanols. SOLUTION: There is provided a method for producing silanols including a reaction step of reacting alkoxysilanes having Si-OR bonds (R represents a hydrocarbon group having 1 to 6 carbon atoms) with water or heavy water in the presence of a catalyst, wherein a method for producing silanols having an Si-OR' bond (R' represents a hydrogen atom or a deuterium atom) is characterized in that the catalyst is an inorganic solid acid catalyst having a regular pore structure. There is also provided novel silanols obtained thereby. SELECTED DRAWING: None COPYRIGHT: (C)2021,JPOandINPIT

O2-enhanced catalytic activity of gold nanoparticles in selective oxidation of hydrosilanes to silanols

O2 acts as a nonconsumed activator for gold nanoparticles (AuNPs) in the oxidation of hydrosilanes to silanols with water under O2 atmosphere, providing an acceleration of more than 200 times relative to the reaction rate under Ar atmosphere. The AuNP catalyst under aerobic conditions exhibits high activity in the oxidation with high turnover numbers (1230000). Various hydrosilanes including less-reactive bulky ones can be converted to the corresponding silanols in excellent yields. Moreover, the present AuNP catalyst is reusable while maintaining the high performance.

Bis(2-thienyl)silanes: new, versatile precursors to arylsilanediols

Silanediols have been shown to be effective bioisosteres for the hydrated carbonyl group. Current methods for the formation of silanediols place a number of constraints on how and where this functionality may be used. A range of arylsilanes that would allow both the formation of arylsilanediols and that are also compatible with multi-step synthetic routes, have been investigated as possible precursors to silanediols. Through this study bis(2-furyl)silanes and, in particular, bis(2-thienyl)silanes have been identified as practical precursors to arylsilanediols.