391-77-5 Usage
Description
4-Chloro-6-fluoroquinoline is a chemical compound belonging to the class of organic compounds known as quinolines and derivatives. It features a quinoline moiety, which is a structure characterized by a pyridine ring fused to a benzene ring. With a molecular formula of C9H5ClFNO, this compound typically appears as a solid and is recognized for its low toxicity. As a derivative of quinoline, 4-Chloro-6-fluoroquinoline holds potential for various applications, particularly in the pharmaceutical and dye production industries, as well as in the synthesis of other chemicals and compounds.
Uses
Used in Pharmaceutical Industry:
4-Chloro-6-fluoroquinoline is used as an intermediate in the synthesis of pharmaceutical compounds for its potential medicinal properties. Its unique structure allows it to be a key component in the development of new drugs, particularly those targeting bacterial infections or other therapeutic areas where quinolines have demonstrated efficacy.
Used in Dye Production:
In the dye industry, 4-Chloro-6-fluoroquinoline is utilized as a precursor or intermediate in the production of various dyes. Its chemical structure contributes to the color and stability of the dyes, making it a valuable component in creating a wide range of colorants for different applications.
Used in Chemical Synthesis:
4-Chloro-6-fluoroquinoline serves as a building block in the synthesis of other complex organic compounds. Its reactivity and structural features make it a versatile starting material for creating a variety of chemical products, including advanced materials, agrochemicals, and specialty chemicals.
Check Digit Verification of cas no
The CAS Registry Mumber 391-77-5 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,9 and 1 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 391-77:
(5*3)+(4*9)+(3*1)+(2*7)+(1*7)=75
75 % 10 = 5
So 391-77-5 is a valid CAS Registry Number.
InChI:InChI=1/C9H5ClFN/c10-8-3-4-12-9-2-1-6(11)5-7(8)9/h1-5H
391-77-5Relevant articles and documents
Preparation method of 4-chloro-6-fluoroquinoline
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Paragraph 0008; 0024; 0025; 0026; 0027, (2017/08/28)
The invention discloses a preparation method of 4-chloro-6-fluoroquinoline. The preparation method comprises the steps: with fluoroaniline as a starting material, firstly, carrying out Michael addition reaction with acrylic acid to obtain an intermediate 3-(4-fluoroanilino)propionic acid; followed by, carrying out a condensation cyclization reaction to obtain an intermediate 6-fluoro-2,3-dihydroquinoline-4(1H)-one; and finally, carrying out halogenation and dehydrogenation reaction to obtain 4-chloro-6-fluoroquinoline. The preparation method has the advantages of wide raw material sources and relatively low cost, thereby having relatively low production cost; at the same time, the preparation method has the advantages of relatively short synthesis route and relatively high yield, especially has mild reaction conditions, has no need of special high temperature equipment, and is suitable for industrialized mass production.
7-Hydroxy-benzo[ij]quinolizine-2-carboxylic acids, intermediates, and a method for their production
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, (2008/06/13)
Intermediates for and a process for preparing certain substituted 6,7-dihydro-7-hydroxy-1-oxo-1H,5H-benzo[ij]quinolizine carboxylic acids is described. The end products are useful antibacterial agents.
