38869-47-5 Usage
Description
1-(4-Methoxyphenyl)piperazine dihydrochloride is a piperazine derivative known for its euphoric and stimulant properties, which are comparable to those produced by amphetamine. It is believed to have a mixed mechanism of action, exhibiting serotonergic and dopamine antagonistic properties similar to 3,4-methylenedioxymethamphetamine. 1-(4-Methoxyphenyl)piperazine dihydrochloride is primarily used for research and forensic purposes, and its metabolism has been described in detail.
Uses
Used in Pharmaceutical Synthesis:
1-(4-Methoxyphenyl)piperazine dihydrochloride serves as an intermediate in the synthesis of Itraconazole (I937500), a widely used antifungal medication. Its role in the synthesis process is crucial for producing the final drug product.
Used in Research and Forensic Analysis:
Due to its chemical properties and effects, 1-(4-Methoxyphenyl)piperazine dihydrochloride is utilized in research settings to study its mechanism of action, particularly its serotonergic and dopamine antagonistic properties. This helps in understanding its potential applications and implications in various fields, including pharmacology and toxicology. Additionally, it is used in forensic analysis to identify and analyze its presence in samples related to substance abuse or criminal investigations.
Check Digit Verification of cas no
The CAS Registry Mumber 38869-47-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,8,8,6 and 9 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 38869-47:
(7*3)+(6*8)+(5*8)+(4*6)+(3*9)+(2*4)+(1*7)=175
175 % 10 = 5
So 38869-47-5 is a valid CAS Registry Number.
InChI:InChI=1/C11H16N2O.2ClH/c1-14-11-4-2-10(3-5-11)13-8-6-12-7-9-13;;/h2-5,12H,6-9H2,1H3;2*1H
38869-47-5Relevant articles and documents
Complete assignments of 1H and 13C NMR data for ten phenylpiperazine derivatives
Xiao, Zhihui,Yuan, Mu,Zhang, Si,Wu, Jun,Qi, Shuhua,Li, Qingxin
, p. 869 - 872 (2005)
Ten phenylpiperazine derivatives were designed and synthesized. The first complete assignments of 1H and 13C NMR chemical shifts for these phenylpiperazine derivatives were achieved by means of 1D and 2D NMR techniques, including 1H-1H COSY, HSQC and HMBC spectra. Copyright
