380193-06-6Relevant articles and documents
Iodine- And TBHP-Promoted Acylation of Benzothiazoles under Metal-Free Conditions
Wang, Bin,Zhang, Qianwei,Guo, Zhongqi,Ablajan, Keyume
, p. 3058 - 3064 (2020/08/28)
A simple protocol for the synthesis of 2-acylbenzothiazoles using aryl ketones and benzothiazoles in the presence of I 2and TBHP is described. Acylation of the benzothiazoles is achieved through a sequence involving oxidation of the aryl ketone to an aryl glyoxal, ring-opening of the benzothiazole followed by condensation of the amino group with the aryl glyoxal, cyclization and oxidation. The method avoids the use of metals and toxic solvents. In addition, this protocol has the advantage of broad scope and provides good to excellent product yields.
A novel self-sequence reaction network involving a set of six reactions in one pot: The synthesis of substituted benzothiazoles from aromatic ketones and anilines
Xue, Wei-Jian,Guo, Ya-Qiong,Gao, Fang-Fang,Li, Hong-Zheng,Wu, An-Xin
supporting information, p. 890 - 893 (2013/04/10)
Employing simple and readily available aromatic ketones and anilines as starting materials resulted in the construction of 2-acylbenzothiazoles via a novel self-sequence reaction network, which assembles six reactions in one pot. The reaction network not only supplied a novel method for constructing complex molecules but also provided a typical example for logical self-organization synthesis.
