3801-06-7

Basic information

• Product Name: Eflone
• Synonyms: FLUOROMETHOLONE ACETATE (200 MG);9-fluoro-11b,17-dihydroxy-6a-methylpregna-1,4-diene-3,20-dione 17-acetate;eflone;fluorometholone acetate;9-fluoro-11beta,17-dihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione 17-acetate;Nolpitantium;FLUROMETHOLONE ACETATE;17-(Acetyloxy)-9-fluoro-11β-hydroxy-6α-methylpregna-1,4-diene-3,20-dione
• CAS NO: 3801-06-7
• Molecular Formula: C₂₄H₃₁FO₅
• Molecular Weight: 418.4983432
• EINECS: 223-270-3
• Product Categories: Intermediates & Fine Chemicals;Pharmaceuticals;Steroids;Hormone Drugs;Inhibitors
• Mol File: 3801-06-7.mol
• Article Data: 0

Chemical Properties

• Melting Point: 230-232°
• Boiling Point: 532.1 °C at 760 mmHg
• Flash Point: 275.6 °C
• Appearance: /
• Density: 1.24 g/cm³
• Vapor Pressure: 1.53E-13mmHg at 25°C
• Refractive Index: 1.556
• Storage Temp.: -20°C Freezer
• Solubility: Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
• PKA: 13.01±0.70(Predicted)
• CAS DataBase Reference: Eflone(CAS DataBase Reference)
• NIST Chemistry Reference: Eflone(3801-06-7)
• EPA Substance Registry System: Eflone(3801-06-7)

Safety Data

• Hazardous Substances Data: 3801-06-7(Hazardous Substances Data)

Usage

Description

Eflone, also known as Fluorometholone Acetate, is a glucocorticoid steroid ester that is formed through the formal condensation of the 17-hydroxy function of fluorometholone with acetic acid. It is characterized by its off-white to pale yellow solid appearance and is commonly known by the brand name Flarex (Alcon).

Uses

Used in Ophthalmology:
Eflone is used as an anti-inflammatory agent for the treatment of steroid-responsive inflammatory conditions of the palpebral and bulbar conjunctiva, cornea, and anterior segment of the eye. Its glucocorticoid properties help in reducing inflammation and providing relief to the affected areas.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, Eflone is utilized for its anti-inflammatory properties to develop medications that target various inflammatory conditions. Its steroidal nature allows it to be an effective treatment option for a range of conditions, making it a valuable asset in the development of new drugs and therapies.
Used in Research and Development:
Eflone's unique chemical properties and anti-inflammatory capabilities make it an important compound in research and development within the scientific community. It is used to study the effects of glucocorticoids on various biological processes and to develop new methods for treating inflammation-related conditions.

InChI:InChI=1/C24H31FO5/c1-13-10-19-17-7-9-23(14(2)26,30-15(3)27)22(17,5)12-20(29)24(19,25)21(4)8-6-16(28)11-18(13)21/h6,8,11,13,17,19-20,29H,7,9-10,12H2,1-5H3/t13-,17-,19-,20-,21-,22-,23-,24-/m0/s1