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  • High Quality 99% L-Alanine,N-[(S)-[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]phenoxyphosphinyl]-, 1-methylethyl ester, (2E)-2-butenedioate (1:1) 379270-38-9 GMP Manufacturer

    Cas No: 379270-38-9

  • USD $ 0.1-0.1 / Gram

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  • 100 Metric Ton/Year

  • Xi'an Xszo Chem Co., Ltd.
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  • 379270-38-9 Structure
  • Basic information

    1. Product Name: GS-7340 (fuMarate)
    2. Synonyms: GS-7340 (fuMarate);L-Alanine, N-[(S)-[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]phenoxyphosphinyl]-, 1-methylethyl ester, (2E)-2-butenedioate (1:1);N-[(S)-[[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]phenoxyphosphinyl]-L-llanine 1-methylethyl ester (2E)-2-butenedioate (1:1);Tenofovir alafenamide fumarate (1:1 salt);Tenofovir alafenamide : fumarate = 1:1)
    3. CAS NO:379270-38-9
    4. Molecular Formula: C21H29N6O5P.C4H4O4
    5. Molecular Weight: 592.55
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 379270-38-9.mol
    9. Article Data: 0
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
    8. Solubility: N/A
    9. CAS DataBase Reference: GS-7340 (fuMarate)(CAS DataBase Reference)
    10. NIST Chemistry Reference: GS-7340 (fuMarate)(379270-38-9)
    11. EPA Substance Registry System: GS-7340 (fuMarate)(379270-38-9)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 379270-38-9(Hazardous Substances Data)

379270-38-9 Usage

Description

GS-7340 (fuMarate), also known as Tenofovir alafenamide fumarate, is a novel and more effective prodrug that has been recently approved for various medical applications. It is a derivative of Tenofovir, a nucleotide reverse transcriptase inhibitor (NtRTI), and is used in combination with other drugs for the treatment and prevention of specific viral infections.

Uses

Used in HIV Prevention:
GS-7340 (fuMarate) is used as a prophylactic agent for the prevention of HIV transmission through the rectum. It is particularly effective when used in combination with other antiretroviral drugs, such as FTC (emtricitabine), to provide a comprehensive approach to reducing the risk of HIV infection.
Used in Chronic Hepatitis B Treatment:
In the medical industry, GS-7340 (fuMarate) is used as an antiviral drug for the treatment of chronic hepatitis B virus (HBV) infection in adults with compensated liver disease. It helps in managing the viral load and preventing the progression of the disease, thereby improving the patient's quality of life and overall health.

Check Digit Verification of cas no

The CAS Registry Mumber 379270-38-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,7,9,2,7 and 0 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 379270-38:
(8*3)+(7*7)+(6*9)+(5*2)+(4*7)+(3*0)+(2*3)+(1*8)=179
179 % 10 = 9
So 379270-38-9 is a valid CAS Registry Number.

379270-38-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name Tenofovir alafenamide fumarate

1.2 Other means of identification

Product number -
Other names GS-7340 fumarate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:379270-38-9 SDS

379270-38-9Upstream product

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