3743-70-2

Basic information

• Product Name: N-(2-hydroxyphenyl)benzamide
• Synonyms: N-(2-hydroxyphenyl)benzamide
• CAS NO: 3743-70-2
• Molecular Formula: C₁₃H₁₁NO₂
• Molecular Weight: 213.23194
• Mol File: 3743-70-2.mol
• Article Data: 49

Chemical Properties

• Boiling Point: 278.1°Cat760mmHg
• Flash Point: 122°C
• Appearance: /
• Density: 1.278g/cm³
• Vapor Pressure: 0.00257mmHg at 25°C
• Refractive Index: 1.675
• CAS DataBase Reference: N-(2-hydroxyphenyl)benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-hydroxyphenyl)benzamide(3743-70-2)
• EPA Substance Registry System: N-(2-hydroxyphenyl)benzamide(3743-70-2)

Safety Data

• Hazardous Substances Data: 3743-70-2(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Tetrahedron Letters, 13, p. 4785, 1972 DOI: 10.1016/S0040-4039(01)94427-2

InChI:InChI=1/C13H11NO2/c15-12-9-5-4-8-11(12)14-13(16)10-6-2-1-3-7-10/h1-9,15H,(H,14,16)

Upstream product

• 64-17-5 ethanol 
• 127-09-3 sodium acetate 
• 91718-58-0 benzoic acid-(2-amino-phenyl ester); hydrochloride 
• 1624-53-9 2-(benzylideneamino)phenol 
• 98-88-4 benzoyl chloride 
• 62-53-3 aniline 
• 94-36-0 dibenzoyl peroxide 
• 4380-77-2 O-phenylbenzohydroxamic acid 
• 6296-59-9 2-(benzamido)phenyl benzoate 
• 7732-18-5 water 
• 95-55-6 2-amino-phenol 
• 93-98-1 N-phenyl benzoyl amide 
• 495-18-1 Benzohydroxamic acid 
• 533-58-4 2-Iodophenol 

Downstream Products

• 860555-71-1 1-benzoylamino-2-propoxycarbonyloxy-benzene 
• 104217-80-3 bis-(2-benzoylamino-phenoxy)-methane 
• 110194-41-7 benzoic acid-[2-(4-nitro-phenacyloxy)-anilide] 
• 833-50-1 2-phenylbenzo[d]oxazole 
• 13316-89-7 benzoic acid-(2-hydroxy-3,5-dinitro-anilide) 
• 1019-90-5 5-chloro-2-phenyl-1,3-benzoxazole 
• 93099-45-7 N-(5-chloro-2-hydroxyphenyl)benzamide 
• 619-58-9 4-iodobenzoic acid 
• 109877-38-5 2-amino-3-hydroxybiphenyl 

Relevant articles and documents

Mechanochemical Synthesis of N-Aryl Amides from O-Protected Hydroxamic Acids

Two robust and efficient mechanochemical protocols for the synthesis of an array of N-arylamides have been developed. This was achieved by a C?N cross-coupling between O-pivaloyl hydroxamic acids and aryl iodides or aryl boronic acids, in the presence of a stoichiometric amount of a copper mediator. The effectiveness of this method is highlighted by the high-yielding (up to 94 %), scalable (up to 8 mmol), and rapid (20 minutes) synthesis of N-aryl amides (15 examples), using a variety of deactivated and sterically encumbered substrates, whilst employing mild conditions and in the absence of solvents. In addition, it was determined that whilst the O-pivaloyl hydroxamic acid precursors can be synthesised mechanochemically, iron contamination originating from the steel jars was found to occur which can hinder the efficacy of this process. Furthermore, 3D printing was used to produce custom milling jars that could successfully accommodate a scaled-up version of the two protocols.

Advanced Polymers from Simple Benzoxazines and Phenols by Ring-Opening Addition Reactions

Simple benzoxazines were mixed and reacted with various phenolics such as phenol, p-nitrophenol, p-cresol, 1,3-dihyroxybenzene (resorcinol), 1,3,5-trihydroxybenzene (phloroglucinol), and N-(2-hydroxyphenyl)benzamide. The influence of these phenolic compou