3739-81-9

Basic information

• Product Name: 1-METHYL-1H-PYRIMIDIN-2-ONE
• Synonyms: 1-METHYL-1H-PYRIMIDIN-2-ONE;1-METHYL-2(1H)-PYRIMIDINONE;1-methylpyrimidin-2-one
• CAS NO: 3739-81-9
• Molecular Formula: C₅H₆N₂O
• Molecular Weight: 110.11394
• Mol File: 3739-81-9.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 180.6 °C at 760 mmHg
• Flash Point: 63 °C
• Appearance: /
• Density: 1.14 g/cm³
• Vapor Pressure: 0.888mmHg at 25°C
• Refractive Index: 1.552
• Storage Temp.: 2-8°C
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• CAS DataBase Reference: 1-METHYL-1H-PYRIMIDIN-2-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-METHYL-1H-PYRIMIDIN-2-ONE(3739-81-9)
• EPA Substance Registry System: 1-METHYL-1H-PYRIMIDIN-2-ONE(3739-81-9)

Safety Data

• Hazardous Substances Data: 3739-81-9(Hazardous Substances Data)

Usage

General Description

1-Methyl-1H-pyrimidin-2-one is a chemical compound with the molecular formula C5H6N2O. It is a pyrimidine derivative with a methyl group attached to the nitrogen atom at position 1. 1-METHYL-1H-PYRIMIDIN-2-ONE is a colorless liquid with a boiling point of 151 degrees Celsius. It is a versatile building block in organic synthesis and can be used as a precursor for various pharmaceuticals and agrochemicals. Additionally, 1-methyl-1H-pyrimidin-2-one has potential applications in the fields of materials science and biochemistry due to its unique structural and chemical properties. As a result, it is a valuable compound in the development of new drugs and materials for various industries.

InChI:InChI=1/C5H6N2O/c1-7-4-2-3-6-5(7)8/h2-4H,1H3

Upstream product

• 186581-53-3 diazomethane 
• 557-01-7 Pyrimidin-2(1H)-one 
• 102-52-3 malonaldehydebis(dimethylacetal) 
• 598-50-5 N-Methylurea 
• 74-88-4 methyl iodide 

Downstream Products

• 77942-46-2 1-methyl-6-phenylethynyl-3,6-dihydropyrimidin-2(1H)-one 
• 615-77-0 1-methyluracil 
• 126126-66-7 1-methyl-4-(pyridin-2-yl)pyrimidin-1-ium-2-olate 
• 126126-65-6 1,1'-Dimethyl-1H,1'H-[4,4']bipyrimidinyl-2,2'-dione 
• 181294-57-5 β-formyl-β-nitroenamine 
• 1086238-26-7 (Z)-3-[(2-ethoxycarbonyl)ethyl]amino-2-nitropropenal 
• 1118541-46-0 (E)-3-[(2-ethoxycarbonyl)ethyl]amino-2-nitropropenal 
• 181294-58-6 N-tert-butyl-β-formyl-β-nitroenamine 
• 1118541-43-7 (E)-3-(2-propen-1-yl)amino-2-nitropropenal 
• 17758-39-3 1-methyl-5-nitropyrimidin-2(1H)-one 

Relevant articles and documents

Synthesis and intramolecular ring transformation of: N, N ′-dialkylated 2,6,9-triazabicyclo[3.3.1]nonadienes

The first and facile synthesis of N,N′-dialkylated 2,6,9-triazabicyclo[3.3.1]nonadienes was achieved by the [4 + 4] self-condensation of β-formyl-β-nitroenamine in the presence of ammonium acetate. The 2,6- A nd 2,9-dialkylated products were found to be interconvertible when dissolved in a solvent. This isomerization proceeds through intramolecular ring transformation via a common intermediate under equilibrium. This journal is

Formylnitroenamines: Useful building blocks for nitrated pyridones and aminopyridines with functional groups

β-Formyl-β-nitroenamines 1 possess both an electrophilic formyl group and a nucleophilic amino group and, therefore, serve as C3N1 building blocks having a nitro group to afford nitropyridones and aminonitropyridines with a functional group at the 3-posit