373380-73-5

Basic information

• Product Name: 3-(2-naphthalen-2-ylmethylphenyl)acrylic acid methyl ester
• Synonyms: 3-(2-naphthalen-2-ylmethylphenyl)acrylic acid methyl ester
• CAS NO: 373380-73-5
• Molecular Weight: 302.373
• Mol File: 373380-73-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-(2-naphthalen-2-ylmethylphenyl)acrylic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2-naphthalen-2-ylmethylphenyl)acrylic acid methyl ester(373380-73-5)
• EPA Substance Registry System: 3-(2-naphthalen-2-ylmethylphenyl)acrylic acid methyl ester(373380-73-5)

Safety Data

• Hazardous Substances Data: 373380-73-5(Hazardous Substances Data)

Upstream product

• 32316-92-0 naphthalene-2-boronic acid 
• 146793-49-9 methyl (E)-3-(2’-(bromomethyl)phenyl)acrylate 
• 939-57-1 (E)-3-(2-methylphenyl)acrylic acid 
• 70625-62-6 methyl (E)-3-(2-methylphenyl)-2-propenoate 

Downstream Products

• 244103-25-1 (E)-3-(2-((naphthalen-3-yl)methyl)phenyl)acrylic acid 
• 244101-02-8 (2E)-N-{[5-bromo-2-(methyloxy)phenyl]sulfonyl}-3-[2-(2-naphthalenylmethyl)phenyl]-2-propenamide 

Relevant articles and documents

Structure-activity relationship of cinnamic acylsulfonamide analogues on the human EP3 prostanoid receptor

Potent and selective antagonists of the human EP3 receptor have been identified. The structure-activity relationship of the chemical series was conducted and we found several analogues displaying sub-nanomolar Ki values at the EP3 receptor and micromolar activities at the EP1, EP2 and EP4 receptors. The effect of added human serum albumin (HSA) on the binding affinity at the EP3 receptor was also investigated.