37319-17-8

Basic information

• Product Name: Elmiron
• Synonyms: Elmiron;Xylan, hydrogen sulfate, sodium salt;xylan polysulfate, sodium;Fibrase;Heoclar;Pentosan polysulfate sodium salt;Sodium xylan polysulfate;Fibrezym
• CAS NO: 37319-17-8
• Molecular Formula: C29H38Na10O50S9
• Molecular Weight: 1705.06472
• Product Categories: Intermediates & Fine Chemicals;Oligosaccharides;Pharmaceuticals;API;API intermediate
• Mol File: 37319-17-8.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Refractive Index: nD20 of 10% aq soln: 1.344
• CAS DataBase Reference: Elmiron(CAS DataBase Reference)
• NIST Chemistry Reference: Elmiron(37319-17-8)
• EPA Substance Registry System: Elmiron(37319-17-8)

Safety Data

• Hazardous Substances Data: 37319-17-8(Hazardous Substances Data)

Usage

Description

Elmiron, also known as Pentosan Polysulfate Sodium, is a synthetic heparin-like drug with anti-inflammatory, antithrombotic, and immunomodulatory properties. It is derived from beechwood and is used for various medical applications due to its unique chemical structure and pharmacological effects.

Uses

Used in Pharmaceutical Industry:
Elmiron is used as an anti-inflammatory agent for the treatment of interstitial cystitis, a chronic bladder condition characterized by urinary frequency, urgency, and pain. It works by inhibiting the release of inflammatory mediators and reducing the permeability of the bladder wall.
Used in Cardiovascular Applications:
Elmiron is used as a therapeutic agent for preserving renal autoregulation in Angiotensin II-infused hypertensive rats. It helps in managing hypertension and reducing inflammation associated with the condition.
Used in Anticancer Applications:
Although not explicitly mentioned in the provided materials, Elmiron has been studied for its potential use in cancer treatment. It has shown promise in inhibiting the growth of certain cancer cells and modulating the immune system to enhance the body's response against cancer.