36276-24-1

Basic information

• Product Name: 3-BROMO-4-METHYL BENZALDEHYDE
• Synonyms: benzaldehyde, 3-bromo-4-methyl-;3-bromo-4-methyl Benzalehyde;3-bromo-4-methylbenzaldehyde(SALTDATA: FREE);3-Bromo-p-tolualdehyde;3-Bromo-4-methylbenzaldehyde 97%
• CAS NO: 36276-24-1
• Molecular Formula: C₈H₇BrO
• Molecular Weight: 199.05
• Product Categories: Aldehydes;Building Blocks;C8;Carbonyl Compounds;Chemical Synthesis;New Products for Chemical Synthesis;Organic Building Blocks
• Mol File: 36276-24-1.mol
• Article Data: 11

Chemical Properties

• Melting Point: 47-52℃
• Boiling Point: 256.9 ºC at 760 mmHg
• Flash Point: 92.2 ºC
• Appearance: /
• Density: 1.49g/cm³
• Vapor Pressure: 0.015mmHg at 25°C
• Refractive Index: 1.597
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• Solubility: soluble in Methanol
• CAS DataBase Reference: 3-BROMO-4-METHYL BENZALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-BROMO-4-METHYL BENZALDEHYDE(36276-24-1)
• EPA Substance Registry System: 3-BROMO-4-METHYL BENZALDEHYDE(36276-24-1)

Safety Data

• Hazard Codes: Xn
• Statements: 22-36/37/38-43
• Safety Statements: 26-36/37
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 36276-24-1(Hazardous Substances Data)

Usage

General Description

3-Bromo-4-methyl benzaldehyde is a chemical compound with the molecular formula C8H7BrO. This organic compound is a brominated derivative of benzaldehyde, which is commonly used in the production of pharmaceuticals, dyes, and perfumes. 3-bromo-4-methyl benzaldehyde is a pale yellow liquid with a strong, sweet odor, and it is primarily used as an intermediate in the synthesis of various organic compounds. It is also known for its role as a building block in the preparation of biologically active molecules and as a reagent in organic synthesis reactions. Additionally, this chemical compound is known for its potential applications in the field of chemical research and development.

InChI:InChI=1/C8H7BrO/c1-6-2-3-7(5-10)4-8(6)9/h2-5H,1H3

Upstream product

• 501420-55-9 3-bromo-N-methoxy-N,4-dimethylbenzamide 
• 7726-95-6 bromine 
• 104-87-0 4-methyl-benzaldehyde 
• 7697-26-9 3-bromo-4-methylbenzoic acid 
• 68120-35-4 (3-bromo-4-methyl-phenyl)-methanol 

Downstream Products

• 36276-25-2 (E)-2-bromo-1-methyl-4-styrylbenzene 
• 95249-73-3 C₁₅H₁₂⁽²⁾H₃BrO 
• 362052-26-4 3-furan-2-yl-4-methyl-benzaldehyde 
• 315187-39-4 9-(3-bromo-4-methylphenyl)-2,3,5,6,7,9-hexahydrothieno[3,2-b]quinolin-8(4H)-one 1,1-dioxide 
• 315188-40-0 4-methyl-3-(methylsulfanyl)benzaldehyde 
• 315188-41-1 4-methyl-3-(methylsulfonyl)benzaldehyde 
• 315188-39-7 2-[4-methyl-3-(methylsulfanyl)phenyl]-1,3-dioxolane 
• 1025799-13-6 2-(3-methanesulfonyl-4-methyl-phenyl)-[1,3]dioxolane 
• 675824-21-2 2-methyl-5-(4,4-dimethyl-2,6-dioxan-1-yl)benzaldehyde 
• 124717-61-9 3-carboxy-4-methylbenzaldehyde ethylene acetal 

Relevant articles and documents

THERAPEUTIC COMPOUNDS

The invention provides compounds of formula I: and salts thereof, as well as pharmaceutical compositions comprising such compounds. The compounds are useful for treating cancers, Alzheimer's disease, and conditions associated with demyelination.

Reduction of Weinreb amides to aldehydes under ambient conditions with magnesium borohydride reagents Dedicated to the memory of Professor Sheldon Shore

Chloromagnesium dimethylaminoborohydride (ClMg+ [H3BNMe2]-, MgAB) is an analogue of the versatile lithium dialkylaminoborohydrides (LAB reagents), prepared by the reaction of dimethylamine-borane with methylmagnesium chloride. MgAB is a partial reducing agent for Weinreb amides under ambient conditions and is complementary to the commonly utilized lithium aluminum hydride (LiAlH4) and diisobutylaluminum hydride (DIBAL) reagents, while exhibiting enhanced chemoselectivity. To prevent over-reduction, the aldehyde products are readily isolated in good yields by forming the sodium bisulfite adducts. Aldehyde products can both be stored and later used as the bisulfite adducts, or can be regenerated from the bisulfite adducts by treatment with aqueous formaldehyde.

SPIRO-SUBSTITUTED OXINDOLE DERIVATIVES HAVING AMPK ACTIVITY

The present invention relates to compounds of formula (I), which have valuable pharmacological properties, in particular are activators of AMPK and which are therefore useful in the treatment of certain disorders that can be prevented or treated by activation of this receptor. The compounds are suitable for treatment and prevention of diseases which can be influenced by this receptor, such as metabolic diseases, in particular diabetes type 2.