360078-88-2

Basic information

• Product Name: (Z)-2-acetylamino-3-(1-naphthyl)-N-[4-(trifluoromethyl)benzyl]-2-propenamide
• CAS NO: 360078-88-2
• Molecular Weight: 412.411
• Mol File: 360078-88-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (Z)-2-acetylamino-3-(1-naphthyl)-N-[4-(trifluoromethyl)benzyl]-2-propenamide(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-2-acetylamino-3-(1-naphthyl)-N-[4-(trifluoromethyl)benzyl]-2-propenamide(360078-88-2)
• EPA Substance Registry System: (Z)-2-acetylamino-3-(1-naphthyl)-N-[4-(trifluoromethyl)benzyl]-2-propenamide(360078-88-2)

Safety Data

• Hazardous Substances Data: 360078-88-2(Hazardous Substances Data)

Upstream product

• 66-77-3 1-naphthaldehyde 
• 3300-51-4 p-Trifluoromethylbenzylamine 
• 128858-50-4 (Z)-2-methyl-4-(naphthalen-1-ylmethylene)oxazol-5(4H)-one 

Relevant articles and documents

Electron transfer-initiated photocyclization of substituted N-acetyl-α-dehydro(1-naphthyl)alanines to 1,2-dihydrobenzo[f]quinolinone derivatives: Scope and limitations

The irradiation of substituted N-acetyl-α-dehydro(1-naphthyl)alanines (1) in MeOH containing triethylamine with Pyrex-filtered light gave 1,2-dihydrobenzo[f]quinolinones (2) in preference to benzo[f]isoquinolines (3) and 1-azetines (4). Analysis of substituent effects on the product compositions revealed that the selectivity of 2 has a strong tendency to decrease with increasing steric bulkiness of the alkyl substituent introduced into the starting (Z)-1. From control and fluorescence quenching experiments it was shown that the photocyclization reaction of 1 affording 2 proceeds by an electron-transfer mechanism. The mechanism of this novel cyclization was discussed mainly based on substituent and solvent effects on both the reactivities of the excited singlet-state 1 and the selectivities of the products 2-4.