360-70-3 Usage
Description
Nandrolone decanoate, also known as nandrolone caprinate, is an alkylated anabolic steroid with a long duration of action and strong anabolic effects. It is a white or almost white, crystalline powder that has been used in the management of anemia of renal insufficiency and as an adjunct therapy in the treatment of senile and postmenopausal osteoporosis. Nandrolone decanoate was patented in Spain in 1959 and granted FDA approval on October 5, 1962. It is also used in the treatment of osteoporosis in postmenopausal women and for some aplastic anemias. The brand name for Nandrolone decanoate includes Durabolin (Organon), Abolon, Activin, Anabolin LA 100, Anador, Anadur, Analone-50, Androlone D 100, Androlone D 50, Decabolin, Deca-Durabolin Decanoate, Deca-Noralone, Docabolin, Fherbolico, Fortabolin, Hybolin-Decanoate, Iebolan, Kabolin, Keratyl, Methybol-Depot, Nandrolone Decanoate, Nordecon, Stenabolin, Sterobolin, and Turinabol-Depot.
Uses
Used in Medical Applications:
Nandrolone decanoate is used as a pharmaceutical agent for the treatment of anemia of renal insufficiency and osteoporosis in postmenopausal women. It is also used for some aplastic anemias, providing anabolic support and helping to manage the symptoms of these conditions.
Used in Controlled Substances:
Nandrolone decanoate is classified as a controlled substance due to its anabolic steroid properties, which can be misused for performance enhancement or bodybuilding purposes. Its controlled status helps regulate its distribution and use, ensuring that it is only used for legitimate medical purposes.
Originator
Deca-Durabolin,Organon,US,1962
Manufacturing Process
1 gram of 19-nortestosterone is dissolved in 3 ml of dry pyridine, after which
the resulting solution is cooled to -20°C. A solution of 1.0 gram of decanoic
acid chloride in 3 ml of dry benzene is added to the cooled solution. The
mixture is maintained at -15°C for 16 hours and then poured into ice water.
The aqueous liquid is extracted with benzene, the benzene solution is washed
with respectively 1 N sodium hydroxide solution, 2 N hydrochloric acid and
with water until neutral reaction.Then the solution is dried on sodium sulfate, filtered, and evaporated to
dryness. The residue, 1.63 grams is dissolved in hexane, this solution is
filtered over 30 grams of neutral aluminum oxide, and evaporated to dryness.
On paper chromatographic investigation it turned out that the obtained 19-
nortestosterone 17-decanoate which at room temperature is an oil consists of
a single compound, according to US Patent 2,998,423.
Therapeutic Function
Anabolic
World Health Organization (WHO)
Nandrolone decanoate, an anabolic steroid, was introduced in
1962. In 1982, low dosage preparations were prohibited in Bangladesh due to
inadmissible promotion of products containing anabolic steroids for malnourished
children. Higher dosage preparations of nandrolone decanoate remain available in
many countries, including Bangladesh, for several highly specific but limited
indications that apply to patients with chronic debilitating and emaciating
diseases, particularly associated with neoplasia and some types of aplastic
anaemia.
Safety Profile
Experimental reproductiveeffects. When heated to decomposition it emits acridsmoke and irritating fumes.
Veterinary Drugs and Treatments
The principle use of nandrolone in veterinary medicine has been to
stimulate erythropoiesis in patients with certain anemias (e.g., secondary
to renal failure, aplastic anemias). It has also been suggested
for use as an appetite stimulant.
Check Digit Verification of cas no
The CAS Registry Mumber 360-70-3 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,6 and 0 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 360-70:
(5*3)+(4*6)+(3*0)+(2*7)+(1*0)=53
53 % 10 = 3
So 360-70-3 is a valid CAS Registry Number.
InChI:InChI=1/C28H44O3/c1-3-4-5-6-7-8-9-10-27(30)31-26-16-15-25-24-13-11-20-19-21(29)12-14-22(20)23(24)17-18-28(25,26)2/h19,22-26H,3-18H2,1-2H3/t22-,23+,24+,25-,26-,28-/m0/s1