35998-79-9

Basic information

• Product Name: Benzenamine, N-(2-furanylmethylene)-, N-oxide
• CAS NO: 35998-79-9
• Molecular Formula: C11H9NO2
• Molecular Weight: 187.198
• Mol File: 35998-79-9.mol
• Article Data: 15

Chemical Properties

• CAS DataBase Reference: Benzenamine, N-(2-furanylmethylene)-, N-oxide(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenamine, N-(2-furanylmethylene)-, N-oxide(35998-79-9)
• EPA Substance Registry System: Benzenamine, N-(2-furanylmethylene)-, N-oxide(35998-79-9)

Safety Data

• Hazardous Substances Data: 35998-79-9(Hazardous Substances Data)

Upstream product

• 98-01-1 furfural 
• 100-65-2 N-Phenylhydroxylamine 
• 586-96-9 Nitrosobenzene 
• 98-95-3 nitrobenzene 

Downstream Products

• 91166-65-3 3-Furan-2-yl-5,7-dimethyl-7H-isoxazolo[3,4-d]pyrimidine-4,6-dione 
• 495-48-7 azoxybenzene 
• 3237-23-8 N-(2-furylmethylene)aniline 
• 98-01-1 furfural 
• 1253959-39-5 (1S,4S)-4-(furan-2-yl)-7-methyl-1,3,5-triphenyl-3,4-dihydro-1H-furo[3,4-d][1,2]oxazine 

Relevant articles and documents

Synthesis and Antimicrobial Evaluation of New Pyrrolo-isoxazolidine Derivatives

In the present study, pyrrolo-isoxazolidines 3(a-l) and 4(a-e), 4g, 4i, 4j have been synthesized by using the 1,3-dipolar cycloaddition reactions of nitrones 1(a-l) with ester substituted N-aryl maleimide (2b). These heterocycles have been obtained in cis and trans diastereomeric forms. The structures of newly synthesized heterocycles have been confirmed from their spectroscopic parameters such as IR,1H NMR,13C NMR and ESI-MS. The in vitro antimicrobial evaluation of these compounds were also investigated. Most of the prepared heterocycles showed significant antimicrobial properties. C3-phenyl substituted products exhibited the remarkable antibacterial behaviours while C3-thienyl/furyl substituted heterocycles proved themselves potent antifungal agents.

Trifluoromethyl Vinyl Sulfide: A Building Block for the Synthesis of CF3S-Containing Isoxazolidines

Trifluoromethyl vinyl sulfide, a potential building block for pharmaceutically and agrochemically relevant products, is prepared and used for the first time in high-pressure-mediated 1,3-dipolar cycloaddition reactions with nitrones to synthesize (trifluoromethyl)sulfanyl isoxazolidines.

Chiral: N, N ′-dioxide/Co(II)-promoted asymmetric 1,3-dipolar cycloaddition of nitrones with methyleneindolinones

A chiral N,N′-dioxide/Co(BF4)2·6H2O complex catalytic system has been developed to efficiently catalyze the asymmetric 1,3-dipolar cycloaddition of nitrones with methyleneindolinones. The corresponding chiral multisubstituted spiroisoxazolidines with three contiguous quaternary-tertiary stereocenters were obtained in moderate to high yields with excellent dr and ee values (up to 97% yield, >19:1 dr and 98% ee).