35086-87-4 Usage
Description
(E)-2-METHYL-3-PHENYL-ACRYLOYL CHLORIDE, with the IUPAC name 2-chloro-3-phenylprop-2-enoyl chloride, is a chemical compound characterized by the formula C10H9ClO. It is a colorless to light yellow liquid with a pungent odor, known for its role as a key intermediate in the synthesis of various pharmaceutical and agrochemical products.
Uses
Used in Pharmaceutical Industry:
(E)-2-METHYL-3-PHENYL-ACRYLOYL CHLORIDE is used as a key intermediate for the synthesis of pharmaceuticals, particularly for the production of anti-cancer drugs and antihistamines. Its acryloyl functionality allows for the creation of compounds with specific therapeutic properties.
Used in Agrochemical Industry:
In the agrochemical sector, (E)-2-METHYL-3-PHENYL-ACRYLOYL CHLORIDE is utilized as a precursor in the synthesis of various agrochemical products, contributing to the development of effective pest control agents and other agricultural chemicals.
Used in Perfume Industry:
(E)-2-METHYL-3-PHENYL-ACRYLOYL CHLORIDE is used as a building block in the production of perfumes, where its unique chemical structure contributes to the creation of distinct and complex fragrances.
Used in Fine Chemicals Production:
(E)-2-METHYL-3-PHENYL-ACRYLOYL CHLORIDE is also employed in the production of other fine chemicals, where its reactivity and functional groups are leveraged to produce specialty chemicals with specific applications.
Used in Polymer and Material Science:
Due to its acryloyl functionality, (E)-2-METHYL-3-PHENYL-ACRYLOYL CHLORIDE is a valuable component in the development of polymers and materials with tailored properties, such as improved strength, flexibility, or chemical resistance.
Safety Note:
(E)-2-METHYL-3-PHENYL-ACRYLOYL CHLORIDE is a potentially hazardous chemical and should be handled with care to avoid irritation to the skin, eyes, and respiratory system. Proper safety measures and personal protective equipment are essential when working with this compound.
Check Digit Verification of cas no
The CAS Registry Mumber 35086-87-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,5,0,8 and 6 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 35086-87:
(7*3)+(6*5)+(5*0)+(4*8)+(3*6)+(2*8)+(1*7)=124
124 % 10 = 4
So 35086-87-4 is a valid CAS Registry Number.
InChI:InChI=1/C10H9ClO/c1-8(10(11)12)7-9-5-3-2-4-6-9/h2-7H,1H3/b8-7+
35086-87-4Relevant articles and documents
Catalytic Enantioselective Synthesis of 3,4-Polyfused Oxindoles with Quaternary All-Carbon Stereocenters: A Rh-Catalyzed C-C Activation Approach
Qiu, Bo,Li, Xiao-Tong,Zhang, Jian-Yu,Zhan, Jun-Ling,Huang, Shuang-Ping,Xu, Tao
, p. 7689 - 7693 (2018)
The first Rh-catalyzed enantioselective synthesis of a 3,4-polyfused oxindole ring system enabled by carboacylation of acrylic amides based on C-C activation is reported. This transformation provides a new entry to access 3,4-polyfused oxindoles bearing q
Photoredox Cyclization of N-Arylacrylamides for Synthesis of Dihydroquinolinones
Liu, Zhaosheng,Zhong, Shuai,Ji, Xiaochen,Deng, Guo-Jun,Huang, Huawen
supporting information, p. 349 - 353 (2021/12/27)
Metal- and additive-free photoredox cyclization of N-arylacrylamides is herein reported that provides a concise access to the formation of dihydroquinolinones. In this protocol, sustainable visible light was used as the energy source, and the organic light-emitting molecule 4CzIPN served as the efficient photocatalyst. This reaction system features exclusive 6-endo-trig cyclization selectivity with a generally good yield of a range of functionalized dihydroquinolinones and dihydrobenzoquinolinones. Mechanistical studies reveal the feasibility of both 1,3-H shift and intersystem crossing of the diradical intermediate.
Synthesis method and applications of N heteroatom polysubstituted benzoquaternary cycloketone
-
Paragraph 0075; 0081-0084, (2020/03/12)
The invention discloses an N heteroatom polysubstituted benzoquaternary cycloketone synthesis method. According to the invention, the synthetic route starts from a known aniline compound A, the hundred g-scale preparation can be achieved, the yield can ac
Copper-Photocatalyzed Contra-Thermodynamic Isomerization of Polarized Alkenes
Bouillon, Jean-Philippe,Brégent, Thibaud,Poisson, Thomas
supporting information, p. 7688 - 7693 (2020/10/09)
The contra-thermodynamic isomerization of α- and β-substituted cinnamate derivatives catalyzed by the Cu(OAc)2/rac-BINAP complex under blue light irradiation is reported. The use of an oxazolidinone template, which favored the complexation of the copper catalyst to the substrate, allowed the E → Z isomerization of the catalytically formed chromophore under simple and robust reaction conditions in good to excellent ratios. The mechanism of this process based on the transient formation of a chromophore was also studied.
